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Image of the Day
Image of the Day: Brain Barrier Balls
Staff | Jun 7, 2017
In a new and improved in vitro model of the blood-brain barrier, scientists allow a milieu of cells to grow together and form multicellular structures.
RNAi’s Future in Drug-Target Screening
Catherine Offord | Apr 17, 2017
A recent CRISPR study contradicted years of RNA interference research on a well-studied cancer drug target. But is it the last nail in the coffin for RNAi as a screening tool?
Experimental MERS Treatments Target Host Cell Receptor
Ashley Yeager | Mar 30, 2017
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
New Drug Target for Three Tropical Diseases
Tracy Vence | Aug 9, 2016
Researchers efficiently clear mice of the parasites that cause leishmaniasis, Chagas disease, and sleeping sickness by inhibiting the parasites’ kinetoplastid proteasomes.
Opinion: Translation Nation
Kathleen Marsman and Lisa McKerracher | Nov 18, 2015
What’s in store for commercialization grants at the Canadian Institutes of Health Research?
Mining Existing Drugs for Ebola Treatments
Rina Shaikh-Lesko | Dec 17, 2014
Researchers hope to repurpose already-approved drugs into potential anti-Ebola therapies.
Tag, You're It
Carina Storrs | Feb 1, 2014
A guide to DNA-encoded libraries for drug discovery
Company Size Won’t Predict Success
Kerry Grens | Oct 23, 2013
New analysis finds that the size of a company is not tied to getting a drug to market.
Week in Review, July 15–19
Jef Akst | Jul 19, 2013
Bias in preclinical research; medical marijuana for kids; a swath of microbial genomes; plastic ocean habitats; rethinking scientific evaluation
NIH to Resurrect Old Drugs
Chris Palmer | Jun 20, 2013
Academic scientists and the pharmaceutical industry will collaborate on a new program to speed up the drug development process.