drug safety, genetics & genomics
Exome Study Reveals Novel Disease-Linked Alleles
Exome Study Reveals Novel Disease-Linked Alleles
Anna Azvolinsky | Dec 22, 2016
By combining whole-exome sequencing data with longitudinal electronic health record information for 50,000 individuals, researchers have identified novel disease associations.
Slideshow: New Species of 2016
Slideshow: New Species of 2016
Jef Akst | Dec 16, 2016
A look at some of the species named this year
New Species of 2016
New Species of 2016
Jef Akst | Dec 16, 2016
From a new Tyrannosaurus and many other dinosaurs to all of the living species named this year, researchers continue to chip away at the planet’s unknown biodiversity.
Induced Pluripotent Stem Cells Show Signs of Donor Age
Induced Pluripotent Stem Cells Show Signs of Donor Age
Ashley P. Taylor | Dec 12, 2016
iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.
Phages Carry Antibiotic Resistance Genes
Phages Carry Antibiotic Resistance Genes
Abby Olena | Dec 8, 2016
Researchers find evidence of antibiotic resistance genes in the DNA of viruses that infect bacteria.
Opinion: Not All Genetic Databases Are Equal
Opinion: Not All Genetic Databases Are Equal
Charles M. Strom | Dec 1, 2016
Sorting out which data sets are clinical-grade is key to helping patients.
Vlad Denic on Exploring New Fields and Failing Successfully
Vlad Denic on Exploring New Fields and Failing Successfully
Ben Andrew Henry | Dec 1, 2016
The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.
The Pangenome: Are Single Reference Genomes Dead?
The Pangenome: Are Single Reference Genomes Dead?
Catherine Offord | Dec 1, 2016
Researchers are abandoning the concept of a list of genes sequenced from a single individual, instead aiming for a way to describe all the genetic variation within a species.
Infographic: Partitioning the Genome
Infographic: Partitioning the Genome
Catherine Offord | Nov 30, 2016
To make sense of the genetic variation within species, researchers are turning to the concept of the pangenome.
Genome Digest
Genome Digest
Ben Andrew Henry | Nov 23, 2016
What researchers are learning as they sequence, map, and decode species’ genomes