Mice Gene-Edited While Still in the Womb
Mice Gene-Edited While Still in the Womb
CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.
Mice Gene-Edited While Still in the Womb
Mice Gene-Edited While Still in the Womb

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

ENCODE, disease & medicine, immunology, genetics & genomics
Prenatal Sequencing for Some Autism Genes May Soon Be Available
Prenatal Sequencing for Some Autism Genes May Soon Be Available
Jessica Wright | Apr 22, 2019
Two studies, taken together, imply that sequencing can identify a genetic cause for ultrasound abnormalities in roughly 10 percent of cases.
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Emma Yasinski | Apr 19, 2019
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
Image of the Day: Pretty Jellies
Image of the Day: Pretty Jellies
Chia-Yi Hou | Apr 19, 2019
The genomes of jellyfish are compared with those of other Cnidarian species that don’t have a free-swimming stage.
Genetic Risk Score Developed for Obesity
Genetic Risk Score Developed for Obesity
Kerry Grens | Apr 18, 2019
The tool weighs millions of variants to determine how susceptible a person is to becoming obese.
Q&amp;A: What to Know About the Drug-Resistant Fungus, <em>Candida auris</em>
Q&A: What to Know About the Drug-Resistant Fungus, Candida auris
Emma Yasinski | Apr 18, 2019
Fungal researcher Christina Cuomo discusses the spread of infections plaguing hospitals across the world.
Image of the Day: Colorful Colonoids
Image of the Day: Colorful Colonoids
Chia-Yi Hou | Apr 18, 2019
Organoids grown from a mouse’s colon will be used to screen drugs for colorectal cancer.
Circulation and Cell Function Revived in Dead Pigs&rsquo; Brains
Circulation and Cell Function Revived in Dead Pigs’ Brains
Chia-Yi Hou | Apr 17, 2019
Researchers develop a system to deliver synthetic blood to isolated brains hours after death.
Gene Therapy Effective for Severe Combined Immunodeficiency
Gene Therapy Effective for Severe Combined Immunodeficiency
Shawna Williams | Apr 17, 2019
Researchers report they’ve found a way to restore immune function in infants with one form of “bubble boy disease.”
Two Patients Treated with CRISPRed Cells in Immunotherapy Trial
Two Patients Treated with CRISPRed Cells in Immunotherapy Trial
Shawna Williams | Apr 16, 2019
One person with multiple myeloma and one with sarcoma are the first so far to receive the genetically engineered T cells in the study.