epigenetics, cell & molecular biology
Learning Opens the Genome
Learning Opens the Genome
Ruth Williams | Jan 17, 2018
Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.
High-Throughput Epigenetics Analyses
High-Throughput Epigenetics Analyses
Jyoti Madhusoodanan | Jan 1, 2018
Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.
Targeting Sodium Channels for Pain Relief
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
Glial Ties to Persistent Pain
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Skin “Remembers” Wounds, Heals Faster the Second Time Around
Skin “Remembers” Wounds, Heals Faster the Second Time Around
Katarina Zimmer | Jan 1, 2018
After an initial wounding, genes needed for repair remain ready for action.
Infographic: A Painful Pathway
Infographic: A Painful Pathway
Catherine Offord | Dec 31, 2017
Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.
Infographic: Two Pain Paths Diverge in the Body
Infographic: Two Pain Paths Diverge in the Body
Mark R. Hutchinson | Dec 31, 2017
The acute pain that results from injury or disease is very different from chronic pain.
Image of the Day: Actin Burst
Image of the Day: Actin Burst
The Scientist Staff | Dec 6, 2017
Researchers are looking at actin polymerization and calcium uptake in human cells to study mitochondrial division.
Researchers Make Knockout Stem Cell Lines in One Step
Researchers Make Knockout Stem Cell Lines in One Step
Ruth Williams | Dec 1, 2017
Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.
Captivated by Chromosomes
Captivated by Chromosomes
Anna Azvolinsky | Dec 1, 2017
Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.