ISTOCK, OONAL
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Questions Raised About “Breakthrough” Therapies’ Clinical Support

Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.

Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.

FDA, cancer, tuberculosis, biobusiness
Cancer Geneticist Quits After Harassment Allegations
Cancer Geneticist Quits After Harassment Allegations
Kerry Grens | Jul 17, 2018
Accusations that Nazneen Rahman bullied employees at the Institute of Cancer Research in the U.K. stretch back 12 years.
CRISPR Gene Editing Deletes, Shuffles More Genes than IntendedCRISPR Gene Editing Deletes, Shuffles More Genes than Intended
CRISPR Gene Editing Deletes, Shuffles More Genes than Intended
Ashley Yeager | Jul 16, 2018
The DNA-cutting enzyme used in the technique is not as precisely targeted as scientists had thought, and investors take notice.
Traitorous Tumor Cells Kill Their Own Kind
Traitorous Tumor Cells Kill Their Own Kind
Ruth Williams | Jul 11, 2018
Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.
Supreme Court Nominee Draws Concern from Environmentalists
Supreme Court Nominee Draws Concern from Environmentalists
Catherine Offord | Jul 10, 2018
President Trump’s pick, Judge Brett Kavanaugh, has often opposed court involvement in environmental and health regulations.
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Katarina Zimmer | Jul 6, 2018
Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.
Opinion: Deductive Science Is Needed for Public Health
Opinion: Deductive Science Is Needed for Public Health
Giuseppe Carruba | Jun 27, 2018
Big data and empirical approaches to understanding diseases provide a limited picture of pathogenesis.
Artificial Intelligence to Boost Liquid Biopsies
Artificial Intelligence to Boost Liquid Biopsies
Claire Asher | Jun 26, 2018
Machine-learning algorithms tuned to detecting cancer DNA in the blood could pave the way for personalized cancer care.
FDA Approves First Marijuana-Derived Drug
FDA Approves First Marijuana-Derived Drug
Shawna Williams | Jun 25, 2018
As the CBD-based medication enters the market, the agency promises a crackdown on producers of cannabidiol products that make unproven claims.
CRISPR Efficiency Tied to Cancer-Causing Process
CRISPR Efficiency Tied to Cancer-Causing Process
Kerry Grens | Jun 11, 2018
Two studies find the genome-editing technique works best when cells have a faulty DNA-damage response that’s frequently present in cancers.