fluorescence

Artist’s rendition of translucent teal proteins comprised of red spherical amino acids

Now AI Can Be Used to Design New Proteins

Kamal Nahas, PhD | | 4 min read

Fluorescence microscopy image of cells expressing fluorescent biosensors. Green and magenta fluorescence is observed outside of the cell nuclei.

Choosing Fluorescent Reagents for Every Live Cell Application

MilliporeSigmaandThe Scientist Creative Services Team | | 4 min read

Learn About the Essential Principles and Practices of Flow Cytometry

Best Practices for Designing and Executing Successful Flow Cytometry Experiments

Fortis Life Sciences | | 1 min read

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Modernizing Drug Discovery with Flow Cytometry

| 1 min read

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 2 min read

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 3 min read

Learn About the Fundamental Principles and Protocols of Flow Cytometry

Streamlining Flow Cytometry Workflows with Best Practices

Bio-Rad Laboratories | | 1 min read

iStock

Illuminating Fluorescent Experiments

Tecan | | 1 min read

iStock

Illuminating Biology with Luminescence

Tecan | | 1 min read

Microscopic image of nerves in the eye, a pathogen, and t cells

Science Snapshot: Eye Immunity

Lisa Winter | | 1 min read

Discover how flow cytometry accelerates drug screening

Adapting Flow Cytometry for Drug Discovery Workflows

Bio-Rad LaboratoriesandThe Scientist Creative Services Team | | 1 min read

An Improved Way to Detect CAR T Cells and SARS-CoV-2-Binding Cells

Technique Talk: An Improved Way to Detect CAR T Cells and SARS-CoV-2-Binding Cells

Available on Demand

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An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Auricular vagal neuromodulation therapy is a non-invasive and non-surgical treatment that could aid cardiovascular disease management, Long COVID relief, and more.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Illustration of a hole in the shape of a dollar sign on a blue background. One character is falling into the hole at the bottom of the “S” while another individual is holding another up at the top of the “S”. The image represents the absence of funding for researchers in biotech with the cancellation of the SBIR/STTR program.

The Federal Government’s Research Innovation Lifeline Has Gone Dark

Congressional inaction has led to the expiration of the federal government’s SBIR/STTR program, cutting off a biotechnology lifeline.

The green zombie virus under the microscope, on a mottled yellow background.

What Are Giant Viruses, and Are They Dangerous?

Lurking in the vast expanse of the ocean and buried deep in the Siberian permafrost, there are giants—not blue whales and mammoths, but giant viruses.

Multimedia

Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

In this webinar, scientists will discuss innovations that are unlocking new insights into immunity.

Advancing Biomarker Discovery for Disease Insights

Advancing Biomarker Discovery for Disease Insights

In this webinar, experts discuss new approaches to biomarker discovery and share the research avenues that elucidate the inner workings of different pathologies.

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue

Research Resources

Podcasts

Webinars

Videos

Infographics

eBooks

Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

In this webinar, scientists will discuss innovations that are unlocking new insights into immunity.

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

A streamlined, automated process helps scientists coordinate site-ready production-level whole genome sequencing results.

Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

In this webinar, learn how scientists are using cutting-edge spatial proteomics technologies to advance their understanding of cellular organization in healthy and diseased tissues.

Products

Product News

Nuclera eProtein Discovery System installed at leading Universities in Taiwan

System strengthens Taiwan’s capabilities in protein drug discovery research

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

The Transferpette® pro expands the Transferpette® family, offering scientists even greater flexibility to match their pipetting preferences and workflow requirements.

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Fast, gentle, and highly specific glycoprotein labeling compatible with downstream immunofluorescence, enabled by next-generation aminooxy chemistry.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.