Thousands of <em>BRCA1</em> Genetic Variants Functionally Characterized
Thousands of BRCA1 Genetic Variants Functionally Characterized
The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.
Thousands of BRCA1 Genetic Variants Functionally Characterized
Thousands of BRCA1 Genetic Variants Functionally Characterized

The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.

The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.

funding, genetics & genomics, cancer
As Bees Specialize, So Does Their DNA Packaging
As Bees Specialize, So Does Their DNA Packaging
Shawna Williams | Sep 11, 2018
A study of chemical tags on histone proteins hints at how the same genome can yield very different animals.
Top Breast Cancer Researcher Didn&rsquo;t Disclose Financial Ties
Top Breast Cancer Researcher Didn’t Disclose Financial Ties
Ashley Yeager | Sep 10, 2018
José Baselga of Memorial Sloan Kettering took millions of dollars from drug and health care companies but did not report the payments in his research articles.
Anti-CRISPR Proteins Found that Block Cas12a Nuclease
Anti-CRISPR Proteins Found that Block Cas12a Nuclease
Ashley Yeager | Sep 6, 2018
Using bioinformatics, two teams of scientists identified inhibitory proteins for Cas9’s relative.
RNA Detection Tool Debate Flares Up at ACS Meeting &nbsp;
RNA Detection Tool Debate Flares Up at ACS Meeting  
Katarina Zimmer | Sep 5, 2018
Researchers have flagged several issues with so-called SmartFlares over the years, and it’s still unclear why they don’t appear to work under certain circumstances.
Early Results of First In Vivo Gene-Editing Trial Encouraging
Early Results of First In Vivo Gene-Editing Trial Encouraging
Kerry Grens | Sep 5, 2018
Two patients who received Sangamo’s zinc finger–based treatment for Hunter syndrome have lower biomarkers of the condition, but no signs of new enzyme production.
Image of the Day: Ocean Wonder
Image of the Day: Ocean Wonder
Sukanya Charuchandra | Sep 4, 2018
Molecules similar to those produced by sea anemones are neuroprotective in a mouse cell model of Alzheimer’s disease.
US Companies Launch CRISPR Clinical Trial
US Companies Launch CRISPR Clinical Trial
Catherine Offord | Sep 3, 2018
The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.
CRISPR Treatment for Duchenne Muscular Dystrophy Helps Dogs
CRISPR Treatment for Duchenne Muscular Dystrophy Helps Dogs
Catherine Offord | Aug 31, 2018
Researchers boosted levels of the dystrophin protein to nearly normal levels in a canine model of the disease.
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Abby Olena | Aug 30, 2018
Even in mice with a busted circadian clock and an unhealthy diet, carefully timed feeding overcomes the rodents’ predispositions for metabolic diseases.