By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
RNA sequencing technology lags far behind researchers’ ability to decode and understand DNA. The COVID-19 pandemic has highlighted this dangerous shortcoming.
Researchers found the relatively high proportion of DNA from a hominin cousin—nearly 5 percent—when they scanned more than 1,000 genomes from 118 distinct ethnic groups.
The genomes of living animals are littered with DNA from long-gone relatives, providing a lens on evolution, past extinctions, and perhaps even solutions to agricultural problems.
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
Rather than relying on samples that need to be shipped in glass vials and on ice, researchers have developed a new method that allows mouse sperm to be sent easily at room temperature using standard mail delivery.
