a giant isopod in an aquarium
Genome Spotlight: Giant Isopod (Bathynomus jamesi)
Christie Wilcox | May 26, 2022
The first high-quality genome for a marine isopod may shed light on how this group of crustaceans adapted to the deep, dark depths of the ocean.
A cockroach clings to the inside of a white mug.
Injecting Cockroaches with CRISPR Gene Edits Their Offspring
Sophie Fessl | May 25, 2022
A new method has allowed researchers to conduct the first gene knock-out and knock-in edits on cockroaches and may extend to many other insects.
MULTI-seq: Single-Cell Genomic Sample Multiplexing Using Lipid-Tagged Indices
MULTI-seq: Single-Cell Genomic Sample Multiplexing Using Lipid-Tagged Indices
The Scientist Creative Services Team | May 9, 2022
In this webinar, Chris McGinnis and Jennifer Silverman discuss how MULTI-seq offers improved sample throughput and data quality.
Illustration of blue shiny mitochondria
Worms Live Longer with Mitochondria Powered by Light: Preprint
Alejandra Manjarrez | May 24, 2022
Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.
Alcohol bottles at a bar
Epigenome Editing Decreases Alcohol Seeking and Anxiety in Rats
Natalia Mesa | May 20, 2022
A CRISPR-based system that reverses epigenetic changes caused by adolescent binge drinking reduces adult addiction-like behaviors in rats, a study finds, suggesting that an epigenomic approach could someday help treat people with alcohol use disorder.
Technique Talk: Purifying Plant-Based Endogenous Biomolecules
Technique Talk: Purifying Plant-Based Endogenous Biomolecules
The Scientist Creative Services Team | May 5, 2022
Learn how reagents affect plant nucleic acids and jeopardize downstream PCR work.
illustration of purple mitochondrion within a cell
Rogue Mitochondria Turn Hermaphroditic Snails Female: Study
Patience Asanga | May 19, 2022
The accidental finding marks the first time a phenomenon called cytoplasmic sterility, known to occur in plants, has been found in animals.
A drawing of pseudostratified gut epithelial cells in the early intestines, cells in red and nucleus in purple.
Move Over Apoptosis: Another Form of Cell Death May Occur in the Gut
Natalia Mesa | May 18, 2022
Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how the gut maintains itself.
Streamline qPCR for Better Data
Streamlining qPCR Through Standardization
The Scientist Creative Services Team, Bio-Rad Laboratories | May 4, 2022
The importance of standardization for research and diagnostic result reproducibility
The fossil tooth found in the Annamite Mountains in Laos
Ancient Tooth Could Be Clue in Denisovan Migration Mystery
Andy Carstens | May 18, 2022
The new fossil from Laos helps answer the question of how some people from Oceania carry DNA from the ancient hominin.
zebrafish (Danio rerio)
Caught on Camera
The Scientist Staff | May 16, 2022
See some of the coolest images recently featured by The Scientist
Cell-Free DNA as Disease Biomarkers
Cell-Free DNA as Disease Biomarkers
The Scientist Creative Services Team | Apr 22, 2022
In this webinar, Stella Goulopoulou and Iwijn de Vlaminck will discuss how they analyze cell-free DNA to identify biomarkers of various diseases and their complications, including preeclampsia, COVID-19, and transplant rejections.
a Hawaiian bobtail squid (Euprymna scolopes) resting on a reflective surface
Reshuffled Genomes May Explain Cephalopods’ Smarts
Sophie Fessl | May 13, 2022
In two related studies, researchers describe huge chromosomal rearrangements and about 500 novel gene clusters in the octopus, squid, and cuttlefish genomes, which they say could help explain how they evolved their extraordinary brains.
Tiliqua rugosa, sleepy lizard, on reddish soil in western Australia
Researchers Probe Genetics Behind a Lizard’s Odd Immune System
Hannah Thomasy | May 10, 2022
Deletions in the sleepy lizard genome leave it without an important type of T cells found in most other vertebrates.
Discover how to avoid PCR inhibition
Crude Samples, Optimal Results
The Scientist Creative Services Team, MilliporeSigma | Apr 19, 2022
Discover how to avoid the PCR inhibitors that lurk in most nucleic acid samples.
Image of a juvenile vaquita
Science Snapshot: Down but Not Out
Lisa Winter | May 6, 2022
Inbreeding depression won’t bring the 10 remaining vaquitas to extinction.
A white mouse huddles with some of her nine-day-old pups.
In Vivo Gene Therapy Cures Infertility in Mice
Dan Robitzski | May 2, 2022
Mice rendered infertile through ovary cell–targeting mutations gave birth to seemingly normal offspring through natural mating after a virus-based gene therapy was injected into their ovaries.
Improve qPCR Efficiency and Reproducibility
The Components of Effective qPCR
The Scientist Creative Services Team, Bio-Rad Laboratories | Apr 18, 2022
Putting the pieces together for molecular diagnostics and infectious disease research
Composite image of earliest humans and wooly mammoths
New Evidence Complicates the Story of the Peopling of the Americas
Emma Yasinski | May 2, 2022
New techniques have shown that people reached the New World far earlier than the long-standing estimate of 13,000 years ago, but scientists still debate exactly when humans arrived on the continent—and how.
Illustrated map showing where evidence was found of the earliest humans
Infographic: Mixed Evidence on Human Occupation of the Americas
Emma Yasinski | May 2, 2022
Diverse lines of evidence point to humans’ presence in the New World long before the dawn of Clovis culture. But rewriting this chapter of human history raises many questions about how these early people came to inhabit these continents.