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A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
Illustration of myelinated neuron axons in light blue, with spindly blue and purple cells interspersed among them.
A Gene Variant Linked to Alzheimer’s May Disrupt Myelin Production
Andy Carstens | Nov 22, 2022 | 5 min read
The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration.
 Learn about analyzing mRNA with direct sequence mapping 
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
Cells with miRNA activity reporter glowing
MicroRNAs Can Boost Gene Expression: Study
Holly Barker | Nov 15, 2022 | 3 min read
The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought.
A colored microscopy image showing cells that are dying in yellow and healthy cells in blue 
Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies
Tess Joosse | Nov 14, 2022 | 2 min read
An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.
Technique Talk: Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
The Scientist Creative Services Team | 1 min read
In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive single-cell resolution in situ genomics.
Blue 3D illustration of X-shaped chromosomes
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa | Nov 11, 2022 | 3 min read
A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 
An excited-looking toddler crawls towards toys while her mother watches on.
Doctors Treat a Rare Genetic Condition Before Patient Is Born
Dan Robitzski | Nov 10, 2022 | 2 min read
Thanks to continued weekly medications, a 16-month-old girl shows no symptoms of a severe genetic disease that typically kills children before they turn two.
Scalable and reproducible solutions in CAR T cell therapy workflows 
Advancing CAR T Cell Research and Development
Bio-Rad | 1 min read
How to develop the best CAR T cell product for preclinical use.
A visualization of a spinal cord with neurons highlighted in red
Scientists Identify Neurons Needed to Walk After Paralysis
Amanda Heidt | Nov 10, 2022 | 3 min read
Nine people with spinal injuries walked again after electrical stimulation, allowing researchers to pinpoint neurons likely underlying their recovery.
bright green plant cells in long diagonal rows
Plant Biologist Jane Silverthorne Dies at 69
Katherine Irving | Nov 8, 2022 | 2 min read
Silverthorne shaped the development of many NSF programs driving innovation in plant biology and agriculture. 
Learn about the need and benefits of automation in sequencing applications 
Making Next-Generation Sequencing Easier 
Roche | 1 min read
Explore the automation revolution in sequencing workflows.
Fernanda, a Fernandina giant tortoise (<em>Chelonoidis phantasticus</em>), was identified in 2019, decades after her species supposedly went extinct.
When an Extinct Species Is Found Alive, What Happens Next?
Andy Carstens | Nov 1, 2022 | 6 min read
Finding a creature in the wild that had been considered long gone brings hope—and quite a bit of uncertainty.
Illustration from the epigenetics and the genome infographic
Infographic: How Epigenetic Marks Can Change the Genome
Katarina Zimmer | Nov 1, 2022 | 2 min read
Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.
Methylation Sequencing to Identify Potential Cancer Biomarkeres&nbsp;
Methylation Sequencing in Cancer Detection
The Scientist Creative Services Team and Twist Bioscience | 1 min read
Discover how efforts to uncover the genome's methylation patterns advance cancer detection.
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
A tropical angelfish&nbsp;
Genome Spotlight: Freshwater Angelfish (Pterophyllum scalare)
Christie Wilcox | Oct 27, 2022 | 4 min read
A high school student uses crowdfunding to produce the first genome assembly for this popular aquarium species, underscoring the increasing feasibility of whole-genome sequencing.
Mosquito on leaf stock photo
Combating Mosquito-Borne Diseases with CRISPR
Niki Spahich, PhD | 4 min read
As alternatives to insecticides, Omar Akbari uses sophisticated genetic engineering methods to solve the world’s mosquito problems.
Pink- and purple-stained cells clustered into glands
Phenotypic Variation in Cancer Cells Often Not Due to Mutations
Jef Akst | Oct 26, 2022 | 3 min read
Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests. 
illustration of neurons in blue and microglia in orange
Ancient Viral DNA Helps Mouse Brains Fight Infection
Natalia Mesa | Oct 24, 2022 | 3 min read
Mammals that give birth to live young may have evolved to make use of the remnants of viruses in their genomes to ward off pathogens, a study suggests. 
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