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genetics

7 days ago | 5 min read

Unbalanced Allele Expression Associated with Mutation, Disease

A study identifies nearly 3,000 genes where one allele tends to be expressed more than the other, but the findings ignited controversy in the field. 
Illustration of DNA double helix with purple background.
A California Chinook Salmon Jumps into a waterfall during spawning season
Feb 1, 2023 | 10+ min read

Geneticists Light Up Debate on Salmon Conservation

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Infographic comparing the fall and spring salmon runs
Infographic: An Incredible Journey
Christie Wilcox, PhD | Feb 1, 2023 | 1 min read
Chinook make their way up the Klamath River every year, but fewer and fewer arrive in the spring.
Timeline summarizing a series of petitions filed about the Chinook salmon
Timeline: An Extended Battle
Christie Wilcox, PhD | Feb 1, 2023 | 3 min read
Various concerned groups have been petitioning NOAA Fisheries to list spring-run Chinook salmon in Oregon and Northern California for over a decade.
Genomic data. Dna test infographic, molecule structure genetic sequencing chart and chromosome architecture genealogy diagram, vector concept stock illustration
Unearthing Hidden Family Secrets: Tracing the Lineage of a Centuries-Old Grand-Mummy
Iris Kulbatski, PhD | 3 min read
Researchers show how a toxic therapy helped identify a mummy using preserved DNA.
A pair of prairie voles (Microtus ochrogaster)
Monogamous Rodents Don’t Need “Love Molecule” To Pair Up
Natalia Mesa, PhD | Jan 27, 2023 | 4 min read
Prairie voles lacking functional receptors for oxytocin form normal social bonds, a finding that could explain the hormone’s clinical failures.
A green and white fish swimming underwater
Rockfish Genes Hold Clues to Human Longevity
Natalia Mesa, PhD | Jan 12, 2023 | 3 min read
By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.
Learn how AI Advances Science 
Breaking Through Big Data Bottlenecks
Tecan | 1 min read
Discover how machine learning helps scientists accelerate their research.  
A younger-looking mouse next to an older-looking one
Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice
Alejandra Manjarrez, PhD | Jan 12, 2023 | 4 min read
Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
3D cubes with DNA sequencing ACGT and double helix
Brush Up: High Throughput Sequencing Technologies
Jennifer Zieba, PhD | 1 min read
High throughput sequencing is a versatile technology that revolutionized the field of genetics.
Artist’s rendering of a reflective metallic DNA double helix.
Humans Are Still Evolving Thanks to Microgenes
Natalia Mesa, PhD | Jan 4, 2023 | 3 min read
A study sheds light on the tiny genes that have evolved in human genomes since we split from our mammalian ancestors.
composite of images from favorite posts
Our Favorite Genetics Stories of 2022
Christie Wilcox, PhD | Dec 22, 2022 | 4 min read
This year’s stories highlight the expanding versatility of genetic techniques and the increasing utility of such research in all life science fields.
 Learn about analyzing mRNA with direct sequence mapping 
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
A fishing cat with a fish in its mouth
Genome Spotlight: Fishing cat (Prionailurus viverrinus)
Christie Wilcox, PhD | Dec 22, 2022 | 5 min read
A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.
Artist’s rendition of two X chromosomes in blue, with a glowing orange line swirling around one.
Male and Female Stem Cells Derived from One Donor in Scientific First
Dan Robitzski | Dec 22, 2022 | 3 min read
Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.
Technique Talk: Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
The Scientist’s Creative Services Team | 1 min read
In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive single-cell resolution in situ genomics.
An artist’s rendition of transcription inside a nucleus
Hypertranscription by Tumors Is Linked to Poorer Cancer Outcomes: Study
Sophie Fessl, PhD | Dec 13, 2022 | 3 min read
The extent to which transcription is higher in tumor cells than in surrounding nontumor cells is associated with bad prognoses in several cancer types.
A fossilized mammoth tusk sitting in a grassy field during sunset 
Woolly Mammoth Genomes Reveal Genetic Adaptations to Cold
Hannah Thomasy | Dec 12, 2022 | 2 min read
Researchers identified mutations in genes that may be involved in fat regulation, fur growth, and morphology.
Scalable and reproducible solutions in CAR T cell therapy workflows 
Advancing CAR T Cell Research and Development
Bio-Rad | 1 min read
How to develop the best CAR T cell product for preclinical use.
Illustration of DNA
Can “Gene Writing” Deliver What Gene Editing Can’t?
Dan Robitzski | Dec 12, 2022 | 10+ min read
A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
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