genetics & genomics, disease & medicine
Optogenetics Meets CRISPR
Optogenetics Meets CRISPR
Jef Akst | Jun 15, 2015
Researchers in Japan have developed a photoactivatable Cas9 nuclease to control CRISPR-based gene editing with the flip of a switch.
TS Live: Genetic Time Machine
TS Live: Genetic Time Machine
Bob Grant | Jun 12, 2015
Piecing together scraps of DNA from a 400,000-year-old hominin femur
Synthetic Biology Entrepreneur Dies
Synthetic Biology Entrepreneur Dies
Kerry Grens | Jun 11, 2015
Austen Heinz, who founded Cambrian Genomics to custom print DNA and had grand ideas about designing organisms, has passed away at age 31.
MERS Sequence Analysis
MERS Sequence Analysis
Tracy Vence | Jun 11, 2015
The strain of the Middle East respiratory syndrome coronavirus currently circulating in South Korea is highly similar to the one in the pathogen’s namesake region.
Disease-Causing Mutations in Healthy People
Disease-Causing Mutations in Healthy People
Amanda B. Keener | Jun 8, 2015
A large-scale genome sequencing effort identifies mutations with disease-causing potential at higher rates than expected.
Mosaic Mutations May Not Be Rare
Mosaic Mutations May Not Be Rare
Anna Azvolinsky | Jun 5, 2015
Somatic mosaicism may be responsible for a larger proportion of genomic variability within humans than previously thought.
The Roots of Schizophrenia
The Roots of Schizophrenia
Jef Akst | Jun 4, 2015
Researchers link disease-associated mutations to excitatory and inhibitory signaling in the brain.
Not So Noncoding
Not So Noncoding
Jenny Rood | Jun 1, 2015
An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.
Silencing Surprise
Silencing Surprise
Jenny Rood | Jun 1, 2015
A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.
New Legs to Stand On
New Legs to Stand On
Mary Beth Aberlin | Jun 1, 2015
Reconstructing the past using ancient DNA