genome, cell & molecular biology, immunology
Signaling Resistance
Signaling Resistance
Jenny Rood | Apr 1, 2015
Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.
Manipulative Microbiomes
Manipulative Microbiomes
Jenny Rood | Apr 1, 2015
Gut bacteria control tumor growth via the mammalian immune system.
Yvonne Saenger: Immunotherapy Pioneer
Yvonne Saenger: Immunotherapy Pioneer
Jef Akst | Apr 1, 2015
Assistant Professor, Department of Medicine, Columbia University. Age: 41
From Many, One
From Many, One
Elena E. Giorgi | Apr 1, 2015
Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?
Resisting Cancer
Resisting Cancer
George Klein | Apr 1, 2015
If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.
Comparing Leprosy Bacteria
Comparing Leprosy Bacteria
Kate Yandell | Mar 27, 2015
Researchers sequence the genome of Mycobacterium lepromatosis, a recently discovered sister species to the primary leprosy-causing bacterium.
Short, Strong Signals
Short, Strong Signals
Ruth Williams | Mar 25, 2015
Methylation increases both the activity and instability of the signaling protein Notch.
Irisin Skepticism Goes Way Back
Irisin Skepticism Goes Way Back
Kerry Grens | Mar 18, 2015
Post-publication peer reviewers had questioned data about the supposed fat-browning enzyme from the get-go.
T Cells of the Skin
T Cells of the Skin
Ruth Williams | Mar 18, 2015
A census of adaptive immune system components in human skin reveals a variety of resident and traveling memory T cells.
Long Live Collagen
Long Live Collagen
Ashley P. Taylor | Mar 1, 2015
Increased collagen expression is a common feature of many different pathways to extended longevity in worms.