genome editing
Man Receives First In Vivo Gene-Editing Therapy
Man Receives First In Vivo Gene-Editing Therapy
Kerry Grens | Nov 15, 2017
The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.
RNA Editing Possible with CRISPR-Cas13
RNA Editing Possible with CRISPR-Cas13
Ruth Williams | Oct 25, 2017
Scientists extend the capabilities of the CRISPR-Cas system to include precise manipulations of RNA sequences in human cells.
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Catherine Offord | Oct 25, 2017
With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.
How Geneticists’ Views Compare to the Public’s on Genome Editing
How Geneticists’ Views Compare to the Public’s on Genome Editing
Bob Grant | Oct 22, 2017
Professionals in the genetics field generally support editing the genomes of somatic cells, mirroring public opinion, but diverge from nonexperts when it comes to germline editing.
Opinion: Genome Editing of Human Embryos Broadens Ethics Discussions
Opinion: Genome Editing of Human Embryos Broadens Ethics Discussions
Françoise Baylis | Oct 10, 2017
Scientists are using a powerful gene editing technique to understand how human embryos develop.
Nonviral CRISPR Delivery a Success
Nonviral CRISPR Delivery a Success
Abby Olena | Oct 2, 2017
Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy. 
Technique Adapted from CRISPR-Cas9 Corrects Mutation in Human Embryos
Technique Adapted from CRISPR-Cas9 Corrects Mutation in Human Embryos
Catherine Offord | Sep 28, 2017
Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.
Most Accurate CRISPR Gene Editing Yet
Most Accurate CRISPR Gene Editing Yet
Kerry Grens | Sep 22, 2017
A tweaked Cas9 nuclease reduces off-target effects to levels below that of previous versions of the enzyme.
CRISPR Used in Human Embryos to Probe Gene Function
CRISPR Used in Human Embryos to Probe Gene Function
Ashley P. Taylor | Sep 20, 2017
OCT4 is necessary for blastocyst formation in the human embryo, researchers report.
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Shawna Williams | Aug 4, 2017
A small patch of engineered cells makes an enzyme that stimulates insulin release.