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Man Receives First In Vivo Gene-Editing Therapy
Kerry Grens | Nov 15, 2017
The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.
RNA Editing Possible with CRISPR-Cas13
Ruth Williams | Oct 25, 2017
Scientists extend the capabilities of the CRISPR-Cas system to include precise manipulations of RNA sequences in human cells.
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Catherine Offord | Oct 25, 2017
With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.
How Geneticists’ Views Compare to the Public’s on Genome Editing
Bob Grant | Oct 22, 2017
Professionals in the genetics field generally support editing the genomes of somatic cells, mirroring public opinion, but diverge from nonexperts when it comes to germline editing.
Opinion: Genome Editing of Human Embryos Broadens Ethics Discussions
Françoise Baylis | Oct 10, 2017
Scientists are using a powerful gene editing technique to understand how human embryos develop.
Nonviral CRISPR Delivery a Success
Abby Olena | Oct 2, 2017
Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy.
Technique Adapted from CRISPR-Cas9 Corrects Mutation in Human Embryos
Catherine Offord | Sep 28, 2017
Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.
Most Accurate CRISPR Gene Editing Yet
Kerry Grens | Sep 22, 2017
A tweaked Cas9 nuclease reduces off-target effects to levels below that of previous versions of the enzyme.
CRISPR Used in Human Embryos to Probe Gene Function
Ashley P. Taylor | Sep 20, 2017
OCT4 is necessary for blastocyst formation in the human embryo, researchers report.
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Shawna Williams | Aug 4, 2017
A small patch of engineered cells makes an enzyme that stimulates insulin release.