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Resistance to HIV Engineered Via CRISPR
Anna Azvolinsky | Aug 3, 2017
Mice transplanted with human hematopoietic stem cells that have an HIV receptor gene,
, disrupted by gene editing allows the animals to ward off HIV infection.
Details Published on CRISPR-treated Embryos
Kerry Grens | Aug 2, 2017
Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.
Scientists Destroy Entire Chromosome with CRISPR
Kerry Grens | Aug 1, 2017
Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.
Human Genetic Variation May Complicate CRISPR
Ashley Yeager | Jul 31, 2017
Slight sequence differences confound target sites in precision genome-editing, a study shows.
Scientists Edit Viable Human Embryos in U.S.
Kerry Grens | Jul 27, 2017
The embryos, whose genes were altered by CRISPR, were not intended for implantation.
Dogs with Duchenne Treated with Gene Therapy
Diana Kwon | Jul 25, 2017
Researchers restored muscle function in animals with muscular dystrophy.
Anti-CRISPR Protein Reduces Off-Target Effects
Diana Kwon | Jul 12, 2017
AcrIIA4, an inhibitor protein from the
bacteriophage, can block DNA from binding to Cas9 during genome editing.
Was a Drop in CRISPR Firms’ Stock Warranted?
Claire Asher | Jun 7, 2017
A study of off-target effects that sparked fear among investors of genome-editing companies receives methodological criticisms.
First In Vivo Human Genome Editing to Be Tested in New Clinical Trial
Abby Olena | May 18, 2017
Sangamo Therapeutics will use zinc finger nucleases to introduce the gene for a missing clotting factor into the livers of men with hemophilia B.
Speaking of Science Policy
Tracy Vence | Feb 21, 2017
Notable quotes from the American Association for the Advancement of Science annual meeting