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Nonviral CRISPR Delivery a Success
Abby Olena | Oct 2, 2017
Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy.
Technique Adapted from CRISPR-Cas9 Corrects Mutation in Human Embryos
Catherine Offord | Sep 28, 2017
Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.
Most Accurate CRISPR Gene Editing Yet
Kerry Grens | Sep 22, 2017
A tweaked Cas9 nuclease reduces off-target effects to levels below that of previous versions of the enzyme.
CRISPR Used in Human Embryos to Probe Gene Function
Ashley P. Taylor | Sep 20, 2017
OCT4 is necessary for blastocyst formation in the human embryo, researchers report.
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Shawna Williams | Aug 4, 2017
A small patch of engineered cells makes an enzyme that stimulates insulin release.
Resistance to HIV Engineered Via CRISPR
Anna Azvolinsky | Aug 3, 2017
Mice transplanted with human hematopoietic stem cells that have an HIV receptor gene,
, disrupted by gene editing allows the animals to ward off HIV infection.
Details Published on CRISPR-treated Embryos
Kerry Grens | Aug 2, 2017
Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.
Scientists Destroy Entire Chromosome with CRISPR
Kerry Grens | Aug 1, 2017
Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.
Human Genetic Variation May Complicate CRISPR
Ashley Yeager | Jul 31, 2017
Slight sequence differences confound target sites in precision genome-editing, a study shows.
Scientists Edit Viable Human Embryos in U.S.
Kerry Grens | Jul 27, 2017
The embryos, whose genes were altered by CRISPR, were not intended for implantation.