germ cells, genetics & genomics
Captivated by Chromosomes
Captivated by Chromosomes
Anna Azvolinsky | Dec 1, 2017
Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.
New Techniques Detail Embryos’ First Hours and Days
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
Infographic: How Embryos Take Control of Their Own Development
Infographic: How Embryos Take Control of Their Own Development
Jef Akst | Nov 30, 2017
The switch from maternal factors involves dynamic reprogramming of the zygotic genome.
The Rising Research Profile of 23andMe
The Rising Research Profile of 23andMe
Catherine Offord | Nov 30, 2017
An exploration of the genetics of earlobe attachment is just the latest collaborative research project to come out of the personal genetic testing company.
Six-Letter DNA Alphabet Produces Proteins in Cells
Six-Letter DNA Alphabet Produces Proteins in Cells
Ruth Williams | Nov 29, 2017
Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.
Man Receives First In Vivo Gene-Editing Therapy
Man Receives First In Vivo Gene-Editing Therapy
Kerry Grens | Nov 15, 2017
The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.
Child Receives Transgenic Skin Over Most of His Body
Child Receives Transgenic Skin Over Most of His Body
Ruth Williams | Nov 8, 2017
A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.
Hormone Loss Prevents Obesity and Diabetes in Mice
Hormone Loss Prevents Obesity and Diabetes in Mice
Abby Olena | Nov 6, 2017
Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.
The Genetic Strategies of Dealing with High Altitude
The Genetic Strategies of Dealing with High Altitude
Abby Olena | Nov 2, 2017
Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.
Opinion: How to Define Cell Type
Opinion: How to Define Cell Type
Fred H. Gage, Sara B. Linker, Tracy A. Bedrosian | Nov 1, 2017
Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.