early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

helminths, disease & medicine
an Aedes scapulari mosquito
Disease-Carrying Mosquito Species Returns to Florida
Shawna Williams | Mar 17, 2021
Aedes scapularis is already established on the peninsula, and researchers predict that its population will continue to spread.
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Lisa Winter | Mar 16, 2021
Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
AstraZeneca, University of Oxford, vaccine, COVID-19, SARS-CoV-2, pandemic, coronavirus, vaccination, safety, Europe
Oxford/AstraZeneca COVID-19 Vaccine on Hold in Some Countries
Asher Jones | Mar 12, 2021
Rollouts of the shot have ground to a halt following reports of blood clots, but health authorities say that these fears are unfounded and vaccination programs should continue.
Gene Therapy for Sickle Cell Not Linked to Cancer, Bluebird Finds
Lisa Winter | Mar 11, 2021
Clinical trials were halted after the treatment’s vector that ferries in the healthy genetic sequence was identified in the genome of a patient’s cancer cells.
Rotonya Carr, University of Pennsylvania, Perelman School of Medicine, underrepresented minority researchers, funding, academic medical centers, COVID-19, pandemic, SARS-CoV-2
Q&A: Unique Circumstances for Minority Scientists During COVID-19
Asher Jones | Mar 10, 2021
Investigators from underrepresented groups have borne the brunt of the disruption to science from the pandemic, according to an opinion piece that outlines ways in which institutions can lessen the damage.
COVID-19, SARS-CoV-2, coronavirus, pandemic, vaccine, vaccine trials, combination, mix and match, immunity, antibodies, T cells, Pfizer, Moderna, AstraZeneca, clinical trials
COVID-19 Vaccine Combos Aim to Boost Immunity
Asher Jones | Mar 9, 2021
Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.
Bispecific Antibodies Treat Cancer in Mouse Models
Abby Olena | Mar 5, 2021
A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.
Interim Report on Origin of SARS-CoV-2 Scrapped by WHO
Lisa Winter | Mar 5, 2021
Instead, the full report will be available in mid-March.
Kids May Suffer from Long COVID, but Data Are Scarce
Jef Akst | Mar 4, 2021
Clinics are popping up around the US to study the sometimes long-lasting effects of SARS-CoV-2 infection in children and teens.
COVID-19, SARS-CoV-2, pandemic, research, reverse genetics, toolkit, antibodies, RNA
Q&A: A Molecular Toolkit to Build SARS-CoV-2 Research Capacity
Asher Jones | Mar 3, 2021
Sam Wilson discusses a user-friendly set of resources that he and his collaborators developed to aid labs pivoting to study COVID-19.
Frontiers Removes Controversial Ivermectin Paper Pre-Publication
Catherine Offord | Mar 2, 2021
A review article containing contested claims about the tropical medicine drug as a COVID-19 treatment was listed as “provisionally accepted” on the journal’s website before being removed this week.
Variant Found in Brazil Could Evade Immunity from Past Infection
Lisa Winter | Mar 2, 2021
The P.1 variant, which has also been detected in five US states, could be responsible for cases of reinfection, according to a preprint.
regeneron monoclonal antibody sars-cov-2 covid-19 pandemic coronavirus neutralization b.1.351 variant south africa REGN10987 casirivimab and REGN10933 imdevimab
Regeneron Cocktail Stumbles Against SARS-CoV-2 Variant in Vitro
Marcus A. Banks | Mar 1, 2021
A treatment of two monoclonal antibodies against SARS-CoV-2 is ninefold less effective in the lab against the B.1.351 variant than against the dominant version of the virus.
COVID-19, SARS-CoV-2, Johnson & Johnson, Pfizer, Moderna, vaccine, vaccination, variant, FDA
US Authorizes a Third COVID-19 Vaccine
Asher Jones | Mar 1, 2021
Johnson & Johnson’s one-shot immunization could reach people’s arms as early as March 2.
Infographic: Envisioning Macrophages
Ashley Yeager | Mar 1, 2021
Researchers find different distributions of the immune cells in young, older, and diseased eyes.
Macrophages of the Human Eye Come into Focus
Ashley Yeager | Mar 1, 2021
Imaged in real time in living people, immune cells at the surface of the retina could serve as biomarkers to detect retinal and possibly neurological diseases and track their progression.
Infographic: How SARS-CoV-2 Immune Responses May Differ by Sex
Catherine Offord | Mar 1, 2021
Males and females show differences in gene expression, cell activation, and antibody production in response to some viral infections, but whether these influence COVID-19 outcomes is still unclear.
COVID-19, coronavirus, SARS-CoV-2, pandemic, virus, vaccine, vaccination, Pfizer, AstraZeneca
COVID-19 Hospitalizations Tank a Month After Vaccines Roll Out
Asher Jones | Feb 23, 2021
Two preliminary reports from the UK provide real-world evidence in support of the Pfizer/BioNTech and Oxford-AstraZeneca vaccines.
Organoids Repair Bile Ducts
Abby Olena | Feb 18, 2021
Researchers determined that when introduced into damaged mouse or donated human livers, these lab-grown tissues could integrate into bile ducts and function normally.