By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.

Researchers identify a role for PIEZO1 in tendon adaptation, and show that people with certain versions of the Piezo1 gene tend to be better jumpers.

Researchers discover surprisingly high levels of genetic diversity among the colorful male morphs of a freshwater fish.

RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.

Researchers found the relatively high proportion of DNA from a hominin cousin—nearly 5 percent—when they scanned more than 1,000 genomes from 118 distinct ethnic groups.

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

Rather than relying on samples that need to be shipped in glass vials and on ice, researchers have developed a new method that allows mouse sperm to be sent easily at room temperature using standard mail delivery.

Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.

Genes associated with preterm birth and protecting the fetus from the mother’s immune system appear to be regulated by HAND2.

A newly identified gene family named “parasitoid killing factor” is found in both insect-infecting viruses and their hosts, although researchers can’t yet tell where they originated.

Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind.

Bettas were likely the first fish welcomed into human homes. Now, scientists are welcoming them into the lab to learn how genes dictate their appearance and behavior.

Not only is the humble fluid a boon for keeping humans cool, it also contains a wealth of biological information.

A comparison of interferon-related genes across 20 primate genomes reveals differences in the speed at which they evolve and new targets for antiviral discovery efforts.

A massive, well-preserved skull discovered in China in the 1930s belongs to a new species called Homo longi, researchers report, but experts remain skeptical about the evidence.

Some of the blood specimens collected in the United States for the NIH’s All of Us research program starting on January 2, 2020, have antibodies against SARS-CoV-2.

The largest study to date of the animals’ genetics provides robust evidence that they are adapting to survive a highly lethal, contagious cancer scientists feared would cause their extinction.

Researchers find that surges in COVID-19 case numbers are associated with deletions in the SARS-CoV-2 genome in an antigenic site of the spike protein. Some of these mutations are present in vaccine breakthrough infections or reinfections.

In a preprint, researchers fill in some of the holes left in the first draft of the human genetic code, published at the turn of the century.