Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures
The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.
Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

immunology
CRISPR Is Overcome When Viruses Gang Up on Bacteria
CRISPR Is Overcome When Viruses Gang Up on Bacteria
Kerry Grens | Jul 19, 2018
Phages that die during bacterial invasion help other viruses defeat the microbes’ immune responses.
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Katarina Zimmer | Jul 6, 2018
Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.
Amazonians Offer Clues to Human Childhood Development
Amazonians Offer Clues to Human Childhood Development
Shawna Williams | Jul 1, 2018
A study of Shuar children in Ecuador provides a window into how the human body responds to infection in the sorts of conditions that shaped our species’ evolution.
Laxative Causes Long-Term Changes to Mouse Microbiome
Laxative Causes Long-Term Changes to Mouse Microbiome
Abby Olena | Jun 14, 2018
Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.
This Flu Season Killed 172 Kids
This Flu Season Killed 172 Kids
Sukanya Charuchandra | Jun 11, 2018
Vaccination reduced the risk of death by two-thirds for children with no other health problems.  
“Public” T-Cell Receptors From Resistant People Fend Off HIV
“Public” T-Cell Receptors From Resistant People Fend Off HIV
Shawna Williams | Jun 8, 2018
The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.
New Insights to Improve CAR T Cells’ Safety
New Insights to Improve CAR T Cells’ Safety
Vicki Brower | Jun 5, 2018
Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.
A T-Cell Tweak Combats Advanced Breast Cancer
A T-Cell Tweak Combats Advanced Breast Cancer
Ashley Yeager | Jun 5, 2018
The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Sukanya Charuchandra | Jun 4, 2018
Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.