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Red and gray round cells floating on a red background. 
Low Intracellular Iron Levels May Keep Blood Stem Cells Young
Alejandra Manjarrez, PhD | Apr 8, 2024 | 3 min read
Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.
A whitish neutrophil with a red multi-lobed nucleus.
Cell Surface RNA Helps Neutrophils Get Around
Holly Barker, PhD | Apr 2, 2024 | 4 min read
A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.
Beyond Cytotoxicity: The Importance of T Cell Memory<br ><br>
Beyond Cytotoxicity: The Importance of T Cell Memory
The Scientist | 1 min read
In this webinar, Grégoire Lauvau and Marcus Buggert will discuss the function and role of memory T cells in health and disease.
A white and tan mother rat watches over several rat pups.&nbsp;
Babies on the Brain
Hannah Thomasy, PhD | Apr 1, 2024 | 2 min read
In rats, motherhood leaves long-term biological signatures in a brain region that is crucial for learning and memory.
Flagellated rod-shaped bacteria live on intestinal tissue.
Clostridia to the Rescue
Shelby Bradford, PhD | Mar 27, 2024 | 3 min read
Some commensal bacteria help shore up intestinal walls in mice, which can prevent food allergies.
3D rendered illustration of the human gastrointestinal tract with an inset close up of the epithelium.
Exploring Preclinical Models for Inflammatory Bowel Disease
The Scientist and Altis Biosystems | 4 min read
Learn how epithelial monolayer models help researchers discover effective therapies and biomarkers for inflammatory bowel diseases.
A pregnant woman blowing her nose.
Viral Immune Responses Suppress a Gestational Hormone
Shelby Bradford, PhD | Mar 25, 2024 | 4 min read
Influenza infection activates a pathway that leads to a detrimental drop in progesterone during pregnancy in mice.
B cells secreting antibodies that target virus particles.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD | Mar 20, 2024 | 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
Accelerating Antibody Discovery for Difficult Targets
Accelerating Antibody Discovery for Difficult Targets
The Scientist | 1 min read
François Romagné will discuss how RNA immunization and single cell screening enhance antibody generation for poorly immunogenic proteins.
Image showing monoclonal antibody treatment
The Resilience of Monoclonal Antibodies and their Makers
Laura Tran, PhD | Mar 15, 2024 | 10+ min read
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
TK
Bat Immune Systems: The Original Antivirus Programs
Hannah Thomasy, PhD | Mar 15, 2024 | 3 min read
Bats stay healthy while hosting some of the world’s deadliest viruses. Scientists are just beginning to understand how.
Good Vibrations: Advancing Cell Therapies
Good Vibrations: Advancing Cell Therapies
The Scientist | 1 min read
In this webinar, Chris Ashdown will discuss how low-intensity vibration affects T cells and how this mechanical stimulation could improve CAR T cell therapy.  
TK
Infographic: Vaccinating Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 1 min read
Cancer vaccines offer the opportunity to use the patient’s own immune system in the fight against tumors.
TK
Infographic: Understanding CAR-T vs TCR Approaches
Danielle Gerhard, PhD | Mar 15, 2024 | 3 min read
Living drugs get a boost from emerging engineering strategies that focus on safety and specificity.
Spatial Multiomics Reveal Microbiome-Linked T Cell Modulations in Human Graft-Versus-Host Disease
Spatial Multiomics Reveal Microbiome-Linked T Cell Modulations in Human Graft-Versus-Host Disease
The Scientist | 1 min read
In this webinar, Benton Berigan will highlight the value of combining multimodal data, including spatial information, to understand complex immunological processes.
3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Discover the Freshness of Frozen PBMCs
Discover the Freshness of Frozen PBMCs
The Scientist | 1 min read
Researchers discuss how peripheral blood mononuclear cell (PBMC) cryopreservation affects T cell activation and immune cell phenotypes.
Robot hand holding glass sphere with glowing fiber neon communication wires
Gazing into Science’s Crystal Ball
Meenakshi Prabhune, PhD | Mar 15, 2024 | 3 min read
Basic research successes offer glimpses into future scientific advancements, but the outcomes are subject to change.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
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