Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.

A study of Shuar children in Ecuador provides a window into how the human body responds to infection in the sorts of conditions that shaped our species’ evolution.

Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.

Vaccination reduced the risk of death by two-thirds for children with no other health problems.  

The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.

Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  

Sequencing of a single gene can spot patients with a dangerous form of mycosis fungoides better than other prognostic tests.