immunology

mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants. 

Researchers shed light on the immunometabolism of respiratory infection, providing an avenue towards safer COVID-19 therapeutics for those affected by metabolic disorders.

New research may make immunotherapy possible for hard-to-treat brain tumors.

By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.

Scientists identified a species of Subdoligranulum that may drive disease.

Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells. 

Engineering of a novel device to treat T1D, featuring local immunosuppression and a vascularized cell reservoir to prolong islet cell survival.

The changes may help explain the link between maternal infection and autism, though more research is needed.

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.

Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.

Self-contained synthetic E. coli resistant to viral infection could prove invaluable to the biotechnology industry by increasing product consistency and reducing safety concerns. 

SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 

Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.

The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease.