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Explore How Stains and Probes Work to Label Cellular Morphology

Biotium | Oct 1, 2024 | 1 min read

Fluorescent probes are key tools for scientists looking at cellular properties or morphology. Use this guide to determine which probe is best for a given situation or experiment.

A baby rhesus macaque against a forest backdrop.

White Blood Cells, Hurricanes, and the Monkeys of Cayo Santiago

Hannah Thomasy, PhD | Oct 1, 2024 | 2 min read

Citizen scientists help monitor monkey immune cells, providing a foundation for future work on stress, sociality, and aging.

Improving T Cell Tumor-Specificity Using Single Cell Co-culture

The Scientist Staff | 1 min read

In this webinar, Edward Han, Jospeh Zenga, and Tyce Kearl will discuss how optofluidic technologies unlock key immuno-oncology insights for translational applications.

Why Do People Have Different Blood Types?

Hannah Thomasy, PhD | Oct 1, 2024 | 2 min read

Humanity’s microscopic foes may be to blame for the ABO polymorphism.

A man in a blue shirt holds a pinkish paper cut out of a pair of lungs.

Genetic Engineering Hides Donor Organs from Host Immune System

Hannah Thomasy, PhD | Sep 30, 2024 | 5 min read

Antigen knockdown prevented organ rejection in minipigs, even in the absence of immunosuppression.

A blue T cell attacks a blue cancer cell

Characterizing Cancer via the Immune Response

The Scientist | 1 min read

Researchers explore the immune system to further understand cancer and illuminate therapy development.

Blue immune cells with yellow spheres of protein surrounding them and landing on them.

Innate Immune Cells Develop Memory with a T Cell Marker

Shelby Bradford, PhD | Sep 30, 2024 | 4 min read

Human innate immune cells that “remember” previous stimulation could provide new insights into chronic inflammatory diseases.

Image of the small intestines and colon within a person with three circular callouts, highlighting different microbes.

Unlocking the Human Microbiome Mysteries: From Cancer to COVID-19

Laura Tran, PhD | Sep 24, 2024 | 4 min read

The microbiome is a dynamic environment that can give researchers the inside scoop on health and disease.

Cell-Based Assays for Immuno-Oncology

Lonza | 1 min read

Cellular immunogenicity and immunotoxicity assays help scientists design, validate, and translate therapeutic research into treatments that weaponize the immune response against cancer.

An illustration of a single cancer cell (in seafoam green) with four white blood cells (in green) attached to it.

The Circadian Clock Tells the Right Time for Immunotherapy

Sahana Sitaraman, PhD | Sep 23, 2024 | 4 min read

Administering immunotherapy when the tumor microenvironment is most susceptible to T cells enhances treatment efficacy in mice.

Image of Lasker laureate Zhijian “James” Chen. He wears glasses and a light blue shirt under a dark blue sweater. He smiles at the camera.

DNA-Sensing Enzyme Wins the 2024 Lasker Award

Laura Tran, PhD | Sep 19, 2024 | 7 min read

Zhijian “James” Chen received this year’s Albert Lasker Award for discovering cGAS, an enzyme which scopes out DNA-based threats and alerts the immune system.

Vaccines and Beyond: Strategies and Technologies for mRNA Therapeutics

The Scientist Staff | 2 min read

An expert panel will discuss mRNA-based vaccines, current approaches and challenges, and how researchers are moving RNA therapeutics forward in exciting new directions.

Two hands holding tweezers and dissecting single points in a DNA sequence.

From CRISPR to Prime Editing: The Evolution of the Genome Editing Revolution

Danielle Gerhard, PhD | Sep 17, 2024 | 5 min read

Even as CRISPR-based tools become a lab staple, scientists strive to tackle the associated technological challenges to improve their efficacy and safety.

3D illustration of a cell with a teal nucleus.

In Search of FACS: The History of Fluorescence Activated Cell Sorting

Shelby Bradford, PhD | Sep 13, 2024 | 10+ min read

In the middle of the 20th century, science disciplines collided and set the stage for a technology that changed cell research.

Spherical viruses with spiked membrane proteins on their surfaces surround larger suspended cancer cells.

Introduction to Oncolytic Virotherapy

Amielle Moreno, PhD | 8 min read

Oncolytic virotherapy selectively attacks tumors and triggers both immediate and long-lasting immune responses.

A wound that is covered with a band-aid.

Why Pain During Wound Healing May be a Good Sign

Sneha Khedkar | Sep 5, 2024 | 4 min read

Sensory neurons grow into injured tissues and modulate the immune system to promote healing.

A syringe inserted into a vial of vaccine.

Engineered Yeast Brew a Vaccine Adjuvant

Sahana Sitaraman, PhD | Sep 3, 2024 | 3 min read

Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.