Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures
The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.
Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

immunology, neurodegeneration, inflammation
CRISPR Is Overcome When Viruses Gang Up on Bacteria
CRISPR Is Overcome When Viruses Gang Up on Bacteria
Kerry Grens | Jul 19, 2018
Phages that die during bacterial invasion help other viruses defeat the microbes’ immune responses.
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Katarina Zimmer | Jul 6, 2018
Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.
Amazonians Offer Clues to Human Childhood Development
Amazonians Offer Clues to Human Childhood Development
Shawna Williams | Jul 1, 2018
A study of Shuar children in Ecuador provides a window into how the human body responds to infection in the sorts of conditions that shaped our species’ evolution.
Herpes Viruses Implicated in Alzheimer’s Disease
Herpes Viruses Implicated in Alzheimer’s Disease
Anna Azvolinsky | Jun 21, 2018

A new study shows that the brains of Alzheimer’s disease patients have a greater viral load, while another study in mice shows infection leads to amyloid-β build up.

Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Sukanya Charuchandra | Jun 20, 2018
The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  
Laxative Causes Long-Term Changes to Mouse Microbiome
Laxative Causes Long-Term Changes to Mouse Microbiome
Abby Olena | Jun 14, 2018
Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.
This Flu Season Killed 172 Kids
This Flu Season Killed 172 Kids
Sukanya Charuchandra | Jun 11, 2018
Vaccination reduced the risk of death by two-thirds for children with no other health problems.  
“Public” T-Cell Receptors From Resistant People Fend Off HIV
“Public” T-Cell Receptors From Resistant People Fend Off HIV
Shawna Williams | Jun 8, 2018
The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.
Mouse Pups Infected With Zika Show Symptoms Into Adulthood
Mouse Pups Infected With Zika Show Symptoms Into Adulthood
Ashley Yeager | Jun 6, 2018
The results suggest the virus could severely alter brain development in infants infected after birth, but blocking a signaling protein early on might ease certain symptoms.