immunology, neurodegeneration, inflammation
Some Antibiotics Rev Up Host Immune Response to Viruses
Some Antibiotics Rev Up Host Immune Response to Viruses
Shawna Williams | Apr 9, 2018
The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.
Opinion: We Have Been Naive About Naive T Cells
Opinion: We Have Been Naive About Naive T Cells
Jos├ę A.M. Borghans, Femke van Wijk, Theo van den Broek | Apr 6, 2018
Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.
Ruth Nussenzweig, Malaria Researcher, Dies
Ruth Nussenzweig, Malaria Researcher, Dies
Jim Daley | Apr 5, 2018
The microbiologist’s research led to the development of the first human malaria vaccine.
Chromosomal Instability Drives Cancer Metastasis
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Jim Daley | Apr 1, 2018
Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.
Macrophages Play a Double Role in Cancer
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018
Errors in segregation during cell division can lead to inflammation in daughter cells.
Antibiotics Increase Mouse Susceptibility to Dengue, West Nile, and Zika
Antibiotics Increase Mouse Susceptibility to Dengue, West Nile, and Zika
Shawna Williams | Mar 27, 2018
The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.
Waning Protection from Vaccination Explains Rise in Mumps Cases
Waning Protection from Vaccination Explains Rise in Mumps Cases
Catherine Offord | Mar 22, 2018
A study finds that the vaccine’s effects wear off as a person ages, suggesting a need for booster shots.
Image of the Day: Aging Brain Cells
Image of the Day: Aging Brain Cells
The Scientist Staff | Mar 13, 2018
Scientists identified a gene involved in the age-related deterioration of mouse neural stem cells.