Metagenomic sequencing can help detect unknown pathogens, but its widespread use faces challenges.

Syphilis is among the oldest known sexually-transmitted infections. Scientists still struggle to detect and treat it.

Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.

The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.

A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.

Pathologist Peyton Rous made a groundbreaking discovery in the early 20th century, but his work wasn’t widely recognized until more than 40 years later. 

The bacterium produces a particular protein that allows it to sneak past the human immune system even while triggering inflammation.

Chlamydia trachomatis, the bacterium that causes chlamydia, hides from the immune system by cloaking itself in the host cell’s membrane then modifying the membrane’s protein composition.

Leaving Twitter, improving science communication, understanding the dangers of avian flu, and more

The “tripledemic” shines a spotlight on viral interference, in which one infection can block another.

Warm nasal cells mount stronger defenses against cold-causing coronaviruses and rhinoviruses than those exposed to cooler temperatures, an in vitro experiment finds.

Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.

Various microbes, including several human pathogens, hijack the cell’s skeleton, membranes, and protein-making machinery to make themselves at home.