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Breaking the Cancer-Obesity Link
Laura W. Bowers, Stephen D. Hursting, Ciara H. O’Flanagan | Nov 1, 2015
Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?
A Complex Disorder
Stephen D. Hursting, Ciara H. O’Flanagan, Laura W. Bowers | Nov 1, 2015
Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.
Bear Study Breaks Down
Kerry Grens | Sep 2, 2015
Authors retract a paper on grizzlies’ metabolism after finding one person made up data.
Week in Review: June 22–26
Jef Akst | Jun 26, 2015
Neanderthal-human hybrid discovered; the neurobiology of fear behavior; and an insulin patch that responds to high glucose levels in mice
Brain’s Role in Browning White Fat
Anna Azvolinsky | Jan 15, 2015
Insulin and leptin act on specialized neurons in the mouse hypothalamus to promote conversion of white to beige fat.
Diabetes “Breakthrough” Breaks Up
Kerry Grens | Oct 27, 2014
A hormone thought to make murine insulin-secreting cells proliferate in mice did not perform in replication studies.
Lab-Made Insulin-Secreting Cells
Bob Grant | Oct 13, 2014
Researchers craft hormone-producing pancreas cells from human embryonic stem cells, paving the way for a cell therapy to treat diabetes.
All In Proportion
Savraj S. Grewal | Mar 2, 2013
insulin-like peptides (dILPs) regulate part of the signaling pathway that helps keep organs growing in proportion during development.
Savraj S. Grewal | Mar 1, 2013
During development, communication between organs determines their relative final size.
Adipose Tissue Metabolism in the Obese
Justin Odegaard and Ajay Chawla | Dec 12, 2012
Fat cells behave differently in obese individuals, causing inflammation and insulin resitance.