lipoprotein lipase deficiency, developmental biology, genetics & genomics
Messing with the Microbiome
Messing with the Microbiome
Ruth Williams | Jul 16, 2017
Two new techniques allow researchers to manipulate the activity of gut bacteria. 
Making the Rounds
Making the Rounds
Catherine Offord | Jul 16, 2017
Circular RNA biogenesis occurs when RNA fragments are bent into closed loops of one or more exons and/or introns.
First Genetic Screen of Pigs Using ENU
First Genetic Screen of Pigs Using ENU
Ashley Yeager | Jul 14, 2017
Using the mutagenic chemical N-ethyl-N-nitrosourea, researchers confirm the role of a gene in a piglet deformity and identify potential models for human diseases. 
Mini-Metagenomics Leads to Microbial Discovery
Mini-Metagenomics Leads to Microbial Discovery
Abby Olena | Jul 14, 2017
Researchers develop a method that combines the strengths of shotgun metagenomics and single-cell genome sequencing in a microfluidics-based platform.
Anti-CRISPR Protein Reduces Off-Target Effects
Anti-CRISPR Protein Reduces Off-Target Effects
Diana Kwon | Jul 12, 2017
AcrIIA4, an inhibitor protein from the Listeria bacteriophage, can block DNA from binding to Cas9 during genome editing.
Snake Sex Determination Dogma Overturned
Snake Sex Determination Dogma Overturned
Abby Olena | Jul 6, 2017
Researchers find that boas and pythons use an XY sex chromosome system, rather than the previously assumed ZW system found in some other snakes.
RNA Protects “Naked” Genomes from Retrotransposons
RNA Protects “Naked” Genomes from Retrotransposons
Shawna Williams | Jun 30, 2017
Transfer RNA fragments prevent jumping genes from hopping around in the mouse embryo, when histone methylation can’t do the job.
Molecular Trigger for Organ Rejection in Mice Identified
Molecular Trigger for Organ Rejection in Mice Identified
Diana Kwon | Jun 27, 2017
The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  
Analysis of Mouse Genes Reveals Novel Disease Models
Analysis of Mouse Genes Reveals Novel Disease Models
Diana Kwon | Jun 26, 2017
The International Mouse Phenotyping Consortium aims to characterize the entire mouse genome, starting first with more than 3,300 genes. 
Ribosomal DNA Copy Numbers Decrease in Some Cancers
Ribosomal DNA Copy Numbers Decrease in Some Cancers
Abby Olena | Jun 22, 2017
An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.