lung cancer, immunology
New Insights to Improve CAR T Cells’ Safety
New Insights to Improve CAR T Cells’ Safety
Vicki Brower | Jun 5, 2018
Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.
A T-Cell Tweak Combats Advanced Breast Cancer
A T-Cell Tweak Combats Advanced Breast Cancer
Ashley Yeager | Jun 5, 2018
The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Sukanya Charuchandra | Jun 4, 2018
Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  
New Liquid Biopsy Detects Cancer at Earlier Stages Than Currently Possible
New Liquid Biopsy Detects Cancer at Earlier Stages Than Currently Possible
Jim Daley | Jun 1, 2018
The test can pick up several types of cancer, including pancreatic and ovarian, years before symptoms appear.
Genetic Screen Predicts T-Cell Lymphoma Aggression
Genetic Screen Predicts T-Cell Lymphoma Aggression
Kerry Grens | May 9, 2018
Sequencing of a single gene can spot patients with a dangerous form of mycosis fungoides better than other prognostic tests.  
Preterm Labor May Be Sparked by Fetal Immune Reaction
Preterm Labor May Be Sparked by Fetal Immune Reaction
Ruth Williams | Apr 25, 2018
Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  
Image of the Day: Immune Cell In Action
Image of the Day: Immune Cell In Action
The Scientist Staff | Apr 23, 2018
By combining two new microscopy technologies, researchers filmed immune cells toiling away in the inner ear of a living zebrafish.
Immune Therapy Improves Lung Cancer Patients’ Survival
Immune Therapy Improves Lung Cancer Patients’ Survival
Jim Daley | Apr 17, 2018
Pembrolizumab combined with chemotherapy nearly doubles survival rates and shrinks tumors in some individuals.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
New Ovarian Cancer Vaccine Shows Promise
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.