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High-Throughput Epigenetics Analyses
Jyoti Madhusoodanan | Jan 1, 2018
Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.
Mitochondrial Networks Explain Why Caloric Restriction Extends Worms’ Lives
Jef Akst | Nov 7, 2017
Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.
Hormone Loss Prevents Obesity and Diabetes in Mice
Abby Olena | Nov 6, 2017
Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.
Olfaction Determines Weight in Mice
Diana Kwon | Jul 5, 2017
Animals lacking a sense of smell stayed thinner than their smelling counterparts, despite eating the same amount.
Mammals May Have a 12-Hour Clock
Ashley Yeager | Jun 6, 2017
Data point to peaks in gene expression in the morning and evening that are distinct from day-night circadian cycles.
Running on Empty
Bob Grant | Jun 1, 2017
Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.
Naked Mole Rats Can Survive Long Periods Without Oxygen
Diana Kwon | Apr 25, 2017
The resilient rodents switch to fructose metabolism in order to survive for up to 18 minutes in anaerobic conditions.
Sweet Trick, Hawkmoths
Bob Grant | Apr 17, 2017
The fast-flying insects convert sugars from nectar into antioxidants, which can help heal the oxidative damage suffered by their hard-working muscles.
Study: Rat Moms’ Diets Affect Offspring Obesity Risk
Jef Akst | Dec 15, 2016
Female rats fed a typical Western diet had offspring that were at higher risk of obesity than moms fed low-fat, high-grain meals.
Altered Microbiome Contributes to Exaggerated Post-Diet Weight Regain in Mice
Tracy Vence | Nov 24, 2016
Obesity-associated microbiome composition can persist after weight loss, affecting the exchange of metabolites between a mouse and its resident bugs, researchers report.