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Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018
Errors in segregation during cell division can lead to inflammation in daughter cells.
Is the Interstitium Really a New Organ?
Abby Olena | Mar 28, 2018
A study confirms that the spaces between cells are fluid-filled, rather than tightly packed with connective tissue, but pathologists say the findings’ implications remain to be seen.
Tumor Organoids Predict How Well Patients Respond to Cancer Drugs
Ruth Williams | Feb 22, 2018
Testing treatments on mini tumors may save time in identifying which therapies work best, a new study shows.
Locally-Injected Immunotherapy Eradicates Tumors in Mice
Diana Kwon | Feb 1, 2018
The treatment also curbed the growth of nearby metastases that did not receive the drug.
Stem Cells Seek Out Tumors Based on Stiffness
Shawna Williams | Jul 26, 2017
The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.
Transgenic Mouse Illuminates Melanoma Metastasis
Abby Olena | Jun 28, 2017
Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels.
Starvation Response Triggers Melanoma Invasion
Catherine Offord | Apr 1, 2017
Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.
Infographic: Inside Melanoma Invasion
Catherine Offord | Mar 31, 2017
See what cytokine activity and cellular starvation have to do with cancer metastasis.