mice, developmental biology, immunology
Researchers Build a Cancer Immunotherapy Without Immune Cells
Researchers Build a Cancer Immunotherapy Without Immune Cells
Abby Olena | Nov 13, 2017
A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 
Image of the Day: Tadpole Prism
Image of the Day: Tadpole Prism
The Scientist Staff, The Scientist Staff | Nov 3, 2017
Scientists are making use of Xenopus tadpoles to study autism risk genes. 
FDA Approves Second CAR T-Cell Therapy
FDA Approves Second CAR T-Cell Therapy
Ashley P. Taylor | Oct 19, 2017
The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 
Compound Found in Red Wine Boosts Immune Cell Function
Compound Found in Red Wine Boosts Immune Cell Function
Catherine Offord | Oct 16, 2017
At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 
Cancers Relapse by Feeding Off Immune Signals
Cancers Relapse by Feeding Off Immune Signals
Shawna Williams | Oct 16, 2017
In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.
Image of the Day: Fragile Brain
Image of the Day: Fragile Brain
The Scientist Staff, The Scientist Staff | Oct 3, 2017
In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.
DNA-Delivered Antibodies Fight Off Lethal Bacterial Infection
DNA-Delivered Antibodies Fight Off Lethal Bacterial Infection
Catherine Offord | Oct 3, 2017
Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.
Microglia Turnover in the Human Brain
Microglia Turnover in the Human Brain
Shawna Williams | Oct 1, 2017
Researchers find that about a quarter of the immune cells are replaced every year.
Macrophages Are the Ultimate Multitaskers
Macrophages Are the Ultimate Multitaskers
Claire Asher | Oct 1, 2017
From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.
Infographic: Macrophages Around the Body
Infographic: Macrophages Around the Body
Claire Asher | Sep 30, 2017
In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.