microbiology, immunology
Study: Microbes from Young Fish Extend Older Fish’s Lives
Study: Microbes from Young Fish Extend Older Fish’s Lives
Kerry Grens | Apr 5, 2017
Recolonizing middle-aged animals with bacteria from younger ones kept killifish alive longer than usual, researchers report.
Gel Scaffolds for Delivery of Immunotherapies
Gel Scaffolds for Delivery of Immunotherapies
Rachel Berkowitz | Apr 1, 2017
Using biocompatible polymers to carry cancer immune therapies directly to the tumor
Making CAR T-Cell Therapy Safer
Making CAR T-Cell Therapy Safer
Catherine Offord | Apr 1, 2017
Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.
Neoantigens Enable Personalized Cancer Immunotherapy
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Targeting Tregs Halts Cancer’s Immune Helpers
Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Targeting Cancer Antigens
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
Infographic: Antibody Cancer Therapy
Infographic: Antibody Cancer Therapy
Ruth Williams | Mar 31, 2017
An experimental technique removes T cells that aid in vitro tumor growth.
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anna Azvolinsky | Mar 30, 2017
Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.
Experimental MERS Treatments Target Host Cell Receptor
Experimental MERS Treatments Target Host Cell Receptor
Ashley Yeager | Mar 30, 2017
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
In Certain Social Bees, Gut Microbiomes Follow Phylogeny
In Certain Social Bees, Gut Microbiomes Follow Phylogeny
Ashley P. Taylor | Mar 29, 2017
Corbiculate bees and their gut-dwelling microbes have been coevolving since the social species evolved from their solitary ancestors around 80 million years ago, scientists suggest.