MODIS, genetics & genomics, disease & medicine
Setbacks and Great Leaps
Setbacks and Great Leaps
Sue Armstrong | Apr 1, 2015
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
The Challenges of Precision
The Challenges of Precision
Adam Marcus | Apr 1, 2015
Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.
Cancer Kismet
Cancer Kismet
Jenny Rood | Apr 1, 2015
Fate mapping allows researchers to follow cancer progression from its cell type of origin.
Two-Faced RNAs
Two-Faced RNAs
Kerry Grens | Apr 1, 2015
The same microRNAs can have opposing roles in cancer.
To Each His Own
To Each His Own
Mary Beth Aberlin | Apr 1, 2015
Cancer treatment becomes more and more personal.
Contributors
Contributors
Jenny Rood | Apr 1, 2015
Meet some of the people featured in the April 2015 issue of The Scientist.
Book Excerpt from <em>p53</em>
Book Excerpt from p53
Sue Armstrong | Apr 1, 2015
In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.
Resisting Cancer
Resisting Cancer
George Klein | Apr 1, 2015
If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.
From Many, One
From Many, One
Elena E. Giorgi | Apr 1, 2015
Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?
Hiding in Plain Sight
Hiding in Plain Sight
Kim Smuga-Otto | Mar 31, 2015
Researchers using metagenomics and single-cell sequencing identify a potential new bacterial phylum.