monoclonal antibodies
Experimental MERS Treatments Target Host Cell Receptor
Experimental MERS Treatments Target Host Cell Receptor
Ashley Yeager | Mar 30, 2017
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
Antibody Treatment Lessens Zika’s Effects in Mice
Antibody Treatment Lessens Zika’s Effects in Mice
Kerry Grens | Nov 7, 2016
When given to pregnant rodents, a human antibody against a viral envelope protein reduces fetal infection, scientists show.
Cautious Optimism About ZMapp Trial
Cautious Optimism About ZMapp Trial
Bob Grant | Feb 25, 2016
The Ebola drug increased survival in a small study, but the effect was not statistically significant.
Single Antibody Protects Macaques from Ebola
Single Antibody Protects Macaques from Ebola
Amanda B. Keener | Feb 25, 2016
The “just right” binding properties of a monoclonal antibody from an Ebolavirus survivor help it neutralize the virus.
In Situ Antibodies
In Situ Antibodies
Jyoti Madhusoodanan | Feb 2, 2016
Compared with systemic injections, localized antibody therapies may be more effective for some indications.
Antibody Alternatives
Antibody Alternatives
Paul Ko Ferrigno, Jane McLeod | Feb 1, 2016
Nucleic acid aptamers and protein scaffolds could change the way researchers study biological processes and treat disease.
Exercises for Your Abs
Exercises for Your Abs
Amber Dance | Feb 1, 2016
Companies make the antibodies, but it’s up to you to make sure they work in your experiments.
Building Better Reagents
Building Better Reagents
Jane McLeod, Paul Ko Ferrigno | Feb 1, 2016
Facing problems of inconsistent, time-consuming, and costly antibody production, some researchers are turning to alternatives to target specific proteins of interest, in the lab and in the clinic.
Amyloid-Targeting Immunotherapy Disrupts Neuronal Function
Amyloid-Targeting Immunotherapy Disrupts Neuronal Function
Karen Zusi | Nov 9, 2015
Some antibodies designed to eliminate the plaques prominent in Alzheimer’s disease can aggravate neuronal hyperactivity in mice.
Two-Faced Proteins May Tackle HIV Reservoirs
Two-Faced Proteins May Tackle HIV Reservoirs
Amanda B. Keener | Oct 21, 2015
Researchers design antibody-like proteins to awaken and destroy HIV holdouts.