A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Closeup of a pair of hands in blue gloves holding a white mouse and injecting it with an amber colored liquid.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Dan Robitzski | Jan 25, 2023 | 6 min read
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
Illuminated drawing of gastrointestinal tract overlayed on woman’s hands and torso
“Gut Feeling” Takes on New Meaning
Iris Kulbatski, PhD | 4 min read
Mechanically sensitive gut cells similar to touch sensors in the skin allow the intestine to feel and assess the physical properties of its contents.
Microscopy image with blue and red neurons, where red indicates neurons involved in a memory engram
Asthma Drug Helps Mice Retrieve Memories “Lost” to Sleep Deprivation
Zunnash Khan | Jan 24, 2023 | 4 min read
A study finds roflumilast can reverse sleep deprivation–induced amnesia in mice, hinting at pathways to treating memory loss in people.
a hand reaches towards a pack of cigarettes
Newly Identified Neural Signature of Drug Craving Could Predict Drug Use
Katherine Irving | Jan 11, 2023 | 4 min read
The signature could one day be used to improve treatment planning for people with substance abuse disorders.
Human brain stock photo
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | 3 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
Artist’s rendition of a neuron silhouetted against a glowing red background.
SNO-y Protein Levels Help Explain Why More Women Develop Alzheimer’s
Dan Robitzski | Jan 6, 2023 | 4 min read
Female postmortem brains contain more S-nitrosylated C3 proteins, likely linked to menopause, which instruct immune cells to kill neuronal synapses.
A man working at a computer late at night
Shift Work Early in Life Results in Increased Stroke Severity in Middle Age
Jennifer Zieba, PhD | 3 min read
Researchers found that shifted sleep/wake cycles in young rats result in increased functional deficits and mortality following stroke later in life.
silhouette of woman's head with lights inside it
Book Excerpt from The Phantom God
John C. Wathey | Jan 2, 2023 | 4 min read
In Chapter 1, “Why Is God Two-Faced?,” author John Wathey argues that the answer to this question is the key to an ethological understanding of religion.
Book cover of The Phantom God by John C. Wathey
Opinion: Neuroscience Could Help Demystify Religious Experience
John C. Wathey | Jan 2, 2023 | 4 min read
If we ask the right questions, modern tools could help researchers solve mysteries such as why many people believe in a God that both provides unconditional love and levies eternal damnation.
Neuronal network with electrical activity of neuron cells in 3D
How Do Neurons Work?
Jennifer Zieba, PhD | 6 min read
Neurons transmit information through the body via chemical signals and electrical impulses.
A collection of images from previous neuroscience articles, including those of an octopus in a chamber, artistic renditions of a brain, brain scans, and an image of neural connections in vitro.
Our Favorite Neuroscience Stories of 2022
Dan Robitzski | Dec 28, 2022 | 4 min read
This year, neuroscience researchers made important discoveries related to how neurodegeneration attacks the human brain, hooked cultured neurons up to machinery to teach them to play a video game, and more.
Collage of faces
Remembering Those We Lost in 2022
Lisa Winter | Dec 26, 2022 | 5 min read
A look at some noteworthy scientists who died this year, leaving behind a legacy of research excellence.
Vector image of swarming locusts in a field
Scents and Sense-Abilities: Using Bug Brainpower to Smell Cancer
Iris Kulbatski, PhD | 4 min read
Scientists use locust brains as living biosensors to perform cancer cell breath tests.
Panels showing different kinds of microglia
Mapping Tool Reveals Microglia’s Shape-Shifting Secrets
Angie Voyles Askham, Spectrum | Dec 14, 2022 | 4 min read
The approach could help test hypotheses about how atypical function of the brain’s immune cells contributes to autism.
Blue glowing neuron projections
Silent Synapses May Provide Plasticity in Adulthood
Holly Barker | Dec 13, 2022 | 4 min read
Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.
X-ray view of human brain with blood vessels
ApoA1 Identified as a Novel Target for ALS Therapy
Jennifer Zieba, PhD | 3 min read
Researchers found that the ApoA1 protein can restore ALS epithelial cell survival in vitro.
Infographic preview
Infographic: A Brain Implant Stops Tumor Growth in Rats
Holly Barker | Dec 12, 2022 | 1 min read
The new, implantable device converts ultrasound waves into electrical energy inside the brain, interfering with tumor cell division.
Render of cancer cells
Implantable Device Zaps Cancer Cells Using Electric Fields
Holly Barker | Dec 12, 2022 | 3 min read
A wireless brain implant inhibits tumor growth in rats, overcoming many design flaws of current devices used to treat glioblastoma.