Bryan Black and Lucas Thal will discuss their experiences screening hiPSC-derived neural cells to understand chronic pain and neuroinflammation.

A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.

Author Lauren Aguirre finds reasons for optimism in the fight against Alzheimer’s disease.

Understanding how the brain coordinates electrical activity could be key to developing more-effective treatments for a variety of brain disorders.

A chronically stressed amygdala can prime the heart to overreact to acute stress events, a new study shows.

Transplanted CAR stem cells persisted long term and showed multilineage engraftment in tissues that harbor HIV.

Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.

After receiving an intraocular injection of the gene for a light-sensitive protein, a 58-year-old man diagnosed with the neurodegenerative eye disease retinitis pigmentosa was able to locate objects on a table using engineered goggles.

The hormone, which is well known for regulating appetite, appears to influence neuronal development—a finding that could shed light on disorders such as autism that involve dysfunctional synapse formation.

The experimental system, developed and tested in just one patient so far, relies on brain signals associated with handwriting to achieve the fastest communication yet seen with BCI.

Researchers identify new motor neuron subgroups and gain insights into amyotrophic lateral sclerosis (ALS).

A dysfunctional lymphatic system, described as a clogging of the brain’s sink, may explain why immunotherapies fail in some Alzheimer’s patients.

A controversial idea from the mid-20th century is attracting renewed attention from researchers developing theories for how cognition arises with or without a brain.

Historical and modern experiments have hinted that unicelluar organisms can learn from their experiences, but the idea still has its critics.

Robert Froemke and Liisa Galea will discuss the neurological changes that occur during motherhood and their effect on behavior and brain health.

Researchers insert functioning cone photoreceptors into the retinas of mice with advanced eye disease, improving their vision.