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Two neurons send electrical signals to each other.

Eavesdropping on Ion Channels Using the Patch Clamp Technique

Laura Tran, PhD | Sep 13, 2024 | 10+ min read

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed.

(Left to right) The first panel is an image of an uneven scale, with the blue male symbol weighing heavier than the red female symbol. The second panel features a mouse with a callout depicting various red and blue lines to represent the estrous cycle. In the third panel, there are images of a mouse, marmoset, and cell culture dish. In the final panel, there is an image of therapeutic pills and gears, representing cognitive function, above a balanced scale. Now the male and female symbols are even.

Infographic: Bridging the Sex Bias Gap

Laura Tran, PhD | Sep 13, 2024 | 3 min read

Researchers challenge a male-dominated field and advocate for more representation of female subjects.

Organoids in Space: The Next Frontier

The Scientist | 2 min read

Researchers take brain training to the next level by launching mini brains into outer space.

Understanding Neurodegenerative Disease with Prion Research

Hannah Thomasy, PhD | Sep 13, 2024 | 9 min read

Molecular neurobiologist Julie Moreno explores the consequences of protein misfolding in the brain.

A colorful image of a brain surrounded by outlines of a woman, rodent, and a marmoset. Lines orbit around the brain and are surrounded by stars.

XX Marks the Spot: Addressing Sex Bias in Neuroscience

Laura Tran, PhD | Sep 13, 2024 | 10+ min read

For years, neuroscience research overlooked female subjects, creating a significant bias. Today, researchers actively rebalance the scales with more inclusive and diverse studies.

Bringing Gene Therapy to the Brain

The Scientist Staff | 1 min read

In this webinar, Douglas Marchuk and Viviana Gradinaru will discuss how scientists can overcome physiological barriers preventing gene therapies from reaching the brain.

An Ode to Stem Cells

Meenakshi Prabhune, PhD | Sep 13, 2024 | 3 min read

Leveraging the versatility of stem cells allows researchers to advance science across multiple disciplines.

Abstract, colorful illustration of the human brain

A Gene Therapy to Treat the FOXG1 Brain Disorder

Niki Spahich, PhD | Sep 12, 2024 | 4 min read

By postnatally providing a transcription factor important for brain development, researchers fixed abnormalities generated in utero in mice.

Two prairie voles are interacting with one another. The vole on the left sniffs the cheek of the vole on the right.

Be My Vole-entine: How Love and Loss Change the Brain

Paige Nicklas | 4 min read

Neuroscientists studying prairie voles discovered that dopamine in the brain gushes when the animals are with their life partners and that loss of a partner erased this neurochemical signature.

A Neural Circuit That Helps Flies Stay on Course

Mariella Bodemeier Loayza Careaga, PhD | Sep 10, 2024 | 5 min read

Two studies tapped into the brain circuitry that allows fruit flies to navigate, offering clues to key principles that may govern navigation in more complex brains.

Illustration of chains of amino acids forming proteins show in light blue against a dark blue background.

Protein Changes in the Brain Could Explain How Neurodevelopment Goes Awry

Claudia Lopez-Lloreda, PhD | Sep 10, 2024 | 4 min read

Long-read sequencing uncovered hundreds of thousands of new isoforms not previously identified during development.

Image showing the legs of multiple people running in the street.

Another Reason to Challenge Yourself at the Gym

Alara Tuncer | 4 min read

In a chronic stress model, challenging exercise reduced anxiety by activating a three-neuron loop across brain regions.

Two scientists look at microscopy data, and one thinks about her own images.

Right Protein, Wrong Pattern

Shelby Bradford, PhD | Sep 2, 2024 | 2 min read

Julia Darby’s tagged chimeric proteins told a convincing story. Later, she learned that they distorted some of the details.

On the left is a brain in blue connect by blue electricity-like lines to a heart in red on the right side of the image.

Can the Brain Help Heal a Broken Heart?

Hannah Thomasy, PhD | Aug 28, 2024 | 6 min read

Stimulation of neural reward pathways may help mice recover from heart attacks.

Viewing the Glioblastoma Tumor Microenvironment at Single Cell Resolution

The Scientist Staff | 1 min read

In this webinar, Matthias Brendel will discuss a new PET approach called scRadiotracing, which involves immunomagnetic cell sorting after in vivo radiotracer injection combined with 3D histology.