Thousands of <em>BRCA1</em> Genetic Variants Functionally Characterized
Thousands of BRCA1 Genetic Variants Functionally Characterized
The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.
Thousands of BRCA1 Genetic Variants Functionally Characterized
Thousands of BRCA1 Genetic Variants Functionally Characterized

The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.

The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.

neuroscience, developmental biology, immunology, disease & medicine
Celebrated Cardiologist Bongani Mayosi Dies
Celebrated Cardiologist Bongani Mayosi Dies
Catherine Offord | Sep 12, 2018
The 51-year-old University of Cape Town researcher had been suffering from depression, and his death has prompted reflection on being a black academic in South Africa.
Microglia Cause Cognitive Decline in Obese Mice
Microglia Cause Cognitive Decline in Obese Mice
Diana Kwon | Sep 10, 2018
The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.
Image of the Day: Switch Gears
Image of the Day: Switch Gears
Sukanya Charuchandra | Sep 10, 2018
A gene responsible for the free-moving, primitive nature of fetal cells is expressed in some breast cancer cells in mice and humans.
Exercise&rsquo;s Benefits to Dementia Can Be Made Chemically
Exercise’s Benefits to Dementia Can Be Made Chemically
Ruth Williams | Sep 6, 2018
Boosting both neurogenesis and a brain-derived growth factor can mimic the cognitive benefits of exercise in a mouse mode of Alzheimer’s disease.
Image of the Day: On the Mend
Image of the Day: On the Mend
Sukanya Charuchandra | Sep 6, 2018
Reprogrammed cells fix wounds in living mice.
AACR Apologizes for Delays in Retracting Papers
AACR Apologizes for Delays in Retracting Papers
Catherine Offord | Sep 5, 2018
Nine of the most recent retractions from AACR journals are for papers coauthored by embattled cancer researcher Bharat Aggarwal.
Adult Cardiac Stem Cells Don&rsquo;t Exist: Study
Adult Cardiac Stem Cells Don’t Exist: Study
Diana Kwon | Sep 5, 2018
A mouse study adds to the growing body of work disputing the ability of progenitor cells to regenerate muscle tissue in adult mammals’ hearts.
Image of the Day: Ocean Wonder
Image of the Day: Ocean Wonder
Sukanya Charuchandra | Sep 4, 2018
Molecules similar to those produced by sea anemones are neuroprotective in a mouse cell model of Alzheimer’s disease.
US Companies Launch CRISPR Clinical Trial
US Companies Launch CRISPR Clinical Trial
Catherine Offord | Sep 3, 2018
The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.