More Cancer Mutations, Better Immunotherapy Outcomes
More Cancer Mutations, Better Immunotherapy Outcomes
Immune checkpoint inhibitors are generally most effective against tumors with more genetic mutations, according to a new study, although the relationship isn’t true for all cancers.
More Cancer Mutations, Better Immunotherapy Outcomes
More Cancer Mutations, Better Immunotherapy Outcomes

Immune checkpoint inhibitors are generally most effective against tumors with more genetic mutations, according to a new study, although the relationship isn’t true for all cancers.

Immune checkpoint inhibitors are generally most effective against tumors with more genetic mutations, according to a new study, although the relationship isn’t true for all cancers.

neuroscience, disease & medicine
Men React to Repeated Painful Experiences Differently than Women Do
Men React to Repeated Painful Experiences Differently than Women Do
Diana Kwon | Jan 14, 2019
Men’s pain tolerance decreases when exposed to a setting where they’ve previously had a painful experience.
Former Head of NIMH, Lewis Judd, Dies
Former Head of NIMH, Lewis Judd, Dies
Kerry Grens | Jan 14, 2019
The UCSD psychiatry researcher championed the concept of mental illness as a neurobiological condition and helped form the US government’s Decade of the Brain initiative.
Image of the Day: Breathe In
Image of the Day: Breathe In
Carolyn Wilke | Jan 14, 2019
Inhalable particles carrying mRNA make mouse lungs glow.
Stem Cell–Derived Neurons from People with Autism Grow Differently
Stem Cell–Derived Neurons from People with Autism Grow Differently
Jef Akst | Jan 11, 2019
Changes in gene expression also hint at how the brains of people with ASD develop differently from those of other people.
Exosomes Linked to Cancer Spread from Chemoresistant Tumors in Mice
Exosomes Linked to Cancer Spread from Chemoresistant Tumors in Mice
Carolyn Wilke | Jan 10, 2019
The vesicles promote metastasis after chemotherapy, but the authors say the results shouldn’t alarm patients and may point to ways to improve treatments.
New York Faces Worst Measles Outbreak in Decades
New York Faces Worst Measles Outbreak in Decades
Catherine Offord | Jan 10, 2019
In one county alone, more than 100 cases have been confirmed since October.
Doubts Raised About Brain Stimulation to Reduce Food Cravings
Doubts Raised About Brain Stimulation to Reduce Food Cravings
Abby Olena | Jan 10, 2019
Despite previous positive reports, researchers didn’t see transcranial direct current stimulation (tDCS) cut back on people’s urges or eating.
US Cancer Death Rate Dropped for 25 Years Starting in 1991
US Cancer Death Rate Dropped for 25 Years Starting in 1991
Carolyn Wilke | Jan 9, 2019
Better treatment and diagnoses have helped more people survive, but economic disparities in outcomes for some preventable cancers have gotten worse.
Newly Identified Virus Similar to Ebola, Marburg
Newly Identified Virus Similar to Ebola, Marburg
Kerry Grens | Jan 9, 2019
Menglà virus, detected in bats in China, infects cells through the same host receptor targeted by the deadly pathogens.