News & Opinion
Top 10 Innovations
Cell & Molecular Biology
Disease & Medicine
Ecology & Environment
Genetics & Genomics
Pharma & Biotech
Image of the Day
New and Improved Organoids Better Resemble Human Brains
Aggie Mika | Nov 16, 2017
More-sophisticated structures lend new insight into how Zika attacks the developing brain.
Image of the Day: Goo for Growing Organoids
Staff, The Scientist Staff | Oct 24, 2017
Scientists engineered a synthetic, nutrient-rich gel that feeds growing organoids as they mature from human pluripotent stem cells into 3-D bowels.
Image of the Day: Lab-Grown Brain
Staff, The Scientist Staff | Oct 12, 2017
Scientists grew organoids that mimic human fetal brains and infected them with the Zika virus to model its neurological effects.
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Shawna Williams | Aug 4, 2017
A small patch of engineered cells makes an enzyme that stimulates insulin release.
Enhancers Drive Pancreatic Cancer Metastasis: Study
Diana Kwon | Jul 27, 2017
Mouse organoids reveal that a protein active during embryonic development joins forces with gene enhancers to revert cancer cells to an earlier developmental state.
Engineered Human Liver Tissue Grows in Mice
Anna Azvolinsky | Jul 19, 2017
Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.
Image of the Day: Liver Buds
Staff | Jun 16, 2017
Using human induced pluripotent stem cells, scientists grew liver organoids and studied gene expression patterns in individual cells to learn more about how these tissues develop.
Image of the Day: Ears-in-a-Dish
Staff | May 1, 2017
Using three-dimensional culture, which allows cells to grow in a ball-shape aggregate, scientists created inner ear organoids containing sensory neurons and hair cells.
Gut Organoid Transplants Produce Colorectal Cancer in Mice
Diana Kwon | Apr 30, 2017
By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease
Developing Brains in Dishes
Ashley P. Taylor | Apr 26, 2017
Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures.