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Image of the Day
Image of the Day: Lab-Grown Brain
Staff, The Scientist Staff | Oct 12, 2017
Scientists grew organoids that mimic human fetal brains and infected them with the Zika virus to model its neurological effects.
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Shawna Williams | Aug 4, 2017
A small patch of engineered cells makes an enzyme that stimulates insulin release.
Enhancers Drive Pancreatic Cancer Metastasis: Study
Diana Kwon | Jul 27, 2017
Mouse organoids reveal that a protein active during embryonic development joins forces with gene enhancers to revert cancer cells to an earlier developmental state.
Engineered Human Liver Tissue Grows in Mice
Anna Azvolinsky | Jul 19, 2017
Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.
Image of the Day: Liver Buds
Staff | Jun 16, 2017
Using human induced pluripotent stem cells, scientists grew liver organoids and studied gene expression patterns in individual cells to learn more about how these tissues develop.
Image of the Day: Ears-in-a-Dish
Staff | May 1, 2017
Using three-dimensional culture, which allows cells to grow in a ball-shape aggregate, scientists created inner ear organoids containing sensory neurons and hair cells.
Gut Organoid Transplants Produce Colorectal Cancer in Mice
Diana Kwon | Apr 30, 2017
By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease
Developing Brains in Dishes
Ashley P. Taylor | Apr 26, 2017
Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures.
Researchers Argue for “Embryoid” Ethics Revamp
Bob Grant | Mar 22, 2017
Scientists issue a call to reconsider the rules governing the creation of tissues, organs, and other structures made possible by recent advances in synthetic biology.
Will Organs-in-a-Dish Ever Replace Animal Models?
Tanya Lewis | Jul 19, 2016
Increasingly sophisticated tissue organoids can model many aspects of disease, but animal studies retain a fundamental role in research, scientists say.