pharmaceuticals, genetics & genomics
Man Receives First In Vivo Gene-Editing Therapy
Man Receives First In Vivo Gene-Editing Therapy
Kerry Grens | Nov 15, 2017
The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.
Child Receives Transgenic Skin Over Most of His Body
Child Receives Transgenic Skin Over Most of His Body
Ruth Williams | Nov 8, 2017
A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.
Hormone Loss Prevents Obesity and Diabetes in Mice
Hormone Loss Prevents Obesity and Diabetes in Mice
Abby Olena | Nov 6, 2017
Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.
RNA Interference Drug Excels in Clinical Trials to Treat Rare Disorder
RNA Interference Drug Excels in Clinical Trials to Treat Rare Disorder
Katarina Zimmer | Nov 3, 2017
If approved, patisiran will be the first RNAi therapeutic on the market. 
The Genetic Strategies of Dealing with High Altitude
The Genetic Strategies of Dealing with High Altitude
Abby Olena | Nov 2, 2017
Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.
Opinion: How to Define Cell Type
Opinion: How to Define Cell Type
Fred H. Gage, Sara B. Linker, Tracy A. Bedrosian | Nov 1, 2017
Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.
Contributors
Contributors
Jef Akst and Bob Grant | Nov 1, 2017
Meet some of the people featured in the November 2017 issue of The Scientist.
Lessons in Memory from a Champ
Lessons in Memory from a Champ
Jef Akst | Nov 1, 2017
A four-time winner of the USA Memory Championship is helping scientists understand how the brain works.
Advancing Techniques Reveal the Brain’s Impressive Diversity
Advancing Techniques Reveal the Brain’s Impressive Diversity
Sara B. Linker, Fred H. Gage, Tracy A. Bedrosian | Nov 1, 2017
No two neurons are alike. What does that mean for brain function?
Infographic: Understanding Our Diverse Brain
Infographic: Understanding Our Diverse Brain
Fred H. Gage, Tracy A. Bedrosian, Sara B. Linker | Oct 31, 2017
Recent advances in single-cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.