illustration of a broken DNA strand
DNA Damage Makes Zebrafish Sleepy
Sophie Fessl | Nov 18, 2021
Buildup of a DNA-repair protein in brain cells spurs shut-eye in the fish, a study finds, and similar results in mice suggest the mechanism is widespread in animals.
Rounded red and green fluorescent cells are visible on a light and dark gray background
Neurons Firing Together Generate Spontaneous Pain
Abby Olena | Nov 10, 2021
Abnormal sympathetic neuron growth leads to simultaneous activation of clusters of sensory neurons, causing the difficult-to-treat sensation.
Photograph of a brown laboratory mouse
Experiment Gone Awry Suggests Novel Way to Combat Hypoxia
Phil Jaekl | Oct 1, 2021
While exploring suspended animation in mice, scientists discover how an enzyme can protect the brain from dangerously low levels of oxygen.
close-up of a retina showing blood vessels and a damaged spot
DNA in Cell Cytoplasm Implicated in Age-Related Blindness
Katarina Zimmer | Sep 29, 2021
A new study suggests that DNA synthesized in the cell cytoplasm drives retinal cell death in an advanced form of age-related macular degeneration, a leading cause of blindness.
white mouse on wheel
Putative Exercise Hormone Irisin Boosts Mouse Brainpower
Sophie Fessl | Sep 10, 2021
Mice lacking irisin didn’t exhibit the cognition improvements that typically follow exercise, and in mouse models of Alzheimer’s disease, treatment with the hormone reduced cognitive decline.
Illustration of a rat with red, white and blue sections
Hormones May Contribute to Asymmetrical Effects of Brain Injury
Catherine Offord | Sep 2, 2021
Researchers studying rats claim to have found a novel connection between damage on one side of the brain and problems with the posture or movement of limbs on the opposite side of the body.
Illustration showing the bodily systems affected by Long COVID
Infographic: Bodily Systems Affected by Long COVID
Sruthi S. Balakrishnan | Sep 1, 2021
Symptoms documented in cases of long COVID are wide ranging and variable.
Immunofluorescence image of human tenocytes (cell nuclei in blue, actin in red) with PIEZO1 protein labeled in green (Scale bar: 20 ?m)
Mechanosensory Protein Helps Tendons Stiffen After Exercise
Catherine Offord | Sep 1, 2021
Researchers identify a role for PIEZO1 in tendon adaptation, and show that people with certain versions of the Piezo1 gene tend to be better jumpers.
A black and white photo of two sets of flowers in test tubes, one of which is wilting
Posies, Poison, and Periods, Early 1920s
Annie Melchor | Sep 1, 2021
Centuries of folklore backed by scientists in the early 1900s have perpetuated the idea that menstruating women can exert dangerous forces.
Illustration of a person sick next to a calendar indicating they've had covid for a long time
Mechanisms of Long COVID Remain Unknown but Data Are Rolling In
Sruthi S. Balakrishnan | Sep 1, 2021
A year and a half into the pandemic, the long-term effects of SARS-CoV-2 infection are garnering more research attention as millions of long COVID patients emerge.
Mouse heart cells that have taken up adipocyte-derived extracellular vesicles (stained red)
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
Black-and-white headshot of Aubrey de Grey
Aubrey de Grey on Leave After Sexual Harassment Allegations
Jef Akst | Aug 11, 2021
Last night, two women publicly accused the famed anti-aging researcher of inappropriately bringing up sex in the workplace, and they say they are not his only victims.
Fat Tissue Reorganizes During Pregnancy
Catherine Offord | Aug 1, 2021
Researchers identify a protein that promotes changes in adipose tissue in vitro and in pregnant mice and may help protect against gestational diabetes in humans.
A black mouse runs on a yellow and green spinning wheel against a blue background
Exercising During Pregnancy Protects Mouse Offspring
Jack J. Lee | Aug 1, 2021
Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.