physiology, genetics & genomics, microbiology
CRISPR Corrects Duchenne-Causing Mutations
CRISPR Corrects Duchenne-Causing Mutations
Anna Azvolinsky | Apr 12, 2017
Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.
Gut Microbes Contribute to Age-Associated Inflammation in Mice
Gut Microbes Contribute to Age-Associated Inflammation in Mice
Abby Olena | Apr 12, 2017
A mouse study reveals a causal link between changes in intestinal microbiota and increasing inflammation as the rodents age.
Behavioral Changes in Mice Given Antibiotics in Early Life
Behavioral Changes in Mice Given Antibiotics in Early Life
Jef Akst | Apr 10, 2017
Mice exposed to low doses of penicillin in utero or as young pups exhibited long-term behavioral differences not seen in their non-exposed counterparts, according to a study.
Clock Gene Mutation Leads to “Night Owl” Behavior
Clock Gene Mutation Leads to “Night Owl” Behavior
Diana Kwon | Apr 9, 2017
Scientists identify a mutation in the CRY1 gene in people with abnormal sleeping patterns.
FDA OKs Marketing of DTC Genetic Health-Risk Tests
FDA OKs Marketing of DTC Genetic Health-Risk Tests
Diana Kwon | Apr 7, 2017
23andMe customers can now receive information about genetic risk for diseases including Parkinson’s and celiac.
Cephalopod Genomes Contain Thousands of Conserved RNA Editing Sites
Cephalopod Genomes Contain Thousands of Conserved RNA Editing Sites
Abby Olena | Apr 6, 2017
Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 
Study: Microbes from Young Fish Extend Older Fish’s Lives
Study: Microbes from Young Fish Extend Older Fish’s Lives
Kerry Grens | Apr 5, 2017
Recolonizing middle-aged animals with bacteria from younger ones kept killifish alive longer than usual, researchers report.
Cross-Sample Sequencing Contamination Galore
Cross-Sample Sequencing Contamination Galore
Ruth Williams | Apr 5, 2017
Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.
Mutations Linked to Secondary Cancers
Mutations Linked to Secondary Cancers
Jef Akst | Apr 4, 2017
Childhood cancer survivors with mutations in certain cancer-risk genes have a higher risk of developing additional neoplasms later in life, according to research presented at the American Association for Cancer Research annual meeting.
Evaluating Epigenome-Targeting Cancer Therapies
Evaluating Epigenome-Targeting Cancer Therapies
Jef Akst | Apr 3, 2017
At the annual American Association for Cancer Research meeting, researchers discuss the importance of understanding the epigenetic contributors to cancer progression and treatment response.