physiology, immunology, developmental biology
Tissue-Clearing Technique Works on Bone
Tissue-Clearing Technique Works on Bone
Kerry Grens | Apr 26, 2017
CLARITY made mouse bones transparent while preserving fluorescent labels so researchers could visualize tagged osteoprogenitors.
Artificial Womb Supports Premature Fetal Lamb Development
Artificial Womb Supports Premature Fetal Lamb Development
Tracy Vence | Apr 25, 2017
The lungs of extremely premature lambs supported in a closed, sterile environment that enables fluid-based gas exchange grow and develop normally, researchers report.
Sweet Trick, Hawkmoths
Sweet Trick, Hawkmoths
Bob Grant | Apr 17, 2017
The fast-flying insects convert sugars from nectar into antioxidants, which can help heal the oxidative damage suffered by their hard-working muscles.
Image of the Day: Stop Signals
Image of the Day: Stop Signals
The Scientist Staff | Apr 16, 2017
Transcytosis, suppression of vesicle traffic across cells, helps reduce permeability in the blood-retinal barrier during development.
Viral Trigger for Celiac Disease?
Viral Trigger for Celiac Disease?
Anna Azvolinsky | Apr 6, 2017
A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 
Gel Scaffolds for Delivery of Immunotherapies
Gel Scaffolds for Delivery of Immunotherapies
Rachel Berkowitz | Apr 1, 2017
Using biocompatible polymers to carry cancer immune therapies directly to the tumor
Making CAR T-Cell Therapy Safer
Making CAR T-Cell Therapy Safer
Catherine Offord | Apr 1, 2017
Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.
Neoantigens Enable Personalized Cancer Immunotherapy
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Targeting Tregs Halts Cancer’s Immune Helpers
Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Targeting Cancer Antigens
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.