physiology, neuroscience, immunology
Image of the Day: Long-Distance Messaging
Image of the Day: Long-Distance Messaging
The Scientist Staff | Apr 6, 2017
After an inflammatory injury occurs in the brain, astrocytes release extracellular vesicles that travel to the liver and trigger an immune response.
Viral Trigger for Celiac Disease?
Viral Trigger for Celiac Disease?
Anna Azvolinsky | Apr 6, 2017
A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 
Image of the Day: Tail Eyes
Image of the Day: Tail Eyes
The Scientist Staff | Apr 2, 2017
Following treatment with a migraine drug, blind tadpoles were able to process visual information through eyes transplanted onto their tails.
Making CAR T-Cell Therapy Safer
Making CAR T-Cell Therapy Safer
Catherine Offord | Apr 1, 2017
Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.
Gel Scaffolds for Delivery of Immunotherapies
Gel Scaffolds for Delivery of Immunotherapies
Rachel Berkowitz | Apr 1, 2017
Using biocompatible polymers to carry cancer immune therapies directly to the tumor
Neoantigens Enable Personalized Cancer Immunotherapy
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Targeting Tregs Halts Cancer’s Immune Helpers
Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Antibody Cancer Therapy
Infographic: Antibody Cancer Therapy
Ruth Williams | Mar 31, 2017
An experimental technique removes T cells that aid in vitro tumor growth.
Infographic: Targeting Cancer Antigens
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anna Azvolinsky | Mar 30, 2017
Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.