Scientist hunched over a lab workbench in exhaustion
Neurotransmitter Buildup May Be Why Your Brain Feels Tired
Performing complex cognitive tasks leads to glutamate accumulating in a key region of the brain, a study finds, which could explain why mental labor is so exhausting.
Neurotransmitter Buildup May Be Why Your Brain Feels Tired
Neurotransmitter Buildup May Be Why Your Brain Feels Tired

Performing complex cognitive tasks leads to glutamate accumulating in a key region of the brain, a study finds, which could explain why mental labor is so exhausting.

Performing complex cognitive tasks leads to glutamate accumulating in a key region of the brain, a study finds, which could explain why mental labor is so exhausting.

ABOVE: © ISTOCK.COM, SKYNESHER
plastids, ecology, neuroscience
Countless bats swarming in the evening dusk
Bat Coronaviruses May Infect Tens of Thousands of People Yearly
Andy Carstens | Aug 10, 2022
Parts of Southeast Asia where human and bat population densities are highest could be infection hotspots, a study finds.
Artistic representation of a brain depicted as a clock on a background with one half in dark blue with yellow stars and one half in light blue with clouds.
Which Neurons Go to Sleep First in Humans? fMRI Can Tell
Alejandra Manjarrez | Aug 9, 2022
By linking blood flow patterns to bioelectric signals in the brains of sleeping volunteers, scientists are studying the order in which brain regions fall asleep and wake up.
Time Traveling Mini-Brains on a Mission to Conquer Space
Time Traveling Mini-Brains on a Mission to Conquer Space
Iris Kulbatski, PhD | Aug 11, 2022
Alysson R. Muotri discusses his launch of brain organoids into outer space and how microgravity enriches our understanding of brain development and disease.
black-and-white brain scan showing tumor
Glioblastoma Cells Imitate Immature Neurons to Invade the Brain
Sophie Fessl | Aug 5, 2022
Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.
smiling woman with hands on hips with blackboard in background
In Deep Water With Gül Dölen
Peter Hess, Spectrum | Aug 4, 2022
A researcher’s existential crisis led to a scientific breakthrough.
Motor neurons, undergoing degeneration in ALS
Mutant T Cells That Drive Amyotrophic Lateral Sclerosis (ALS) Progression May React To a Brain Antigen
Nele Haelterman, PhD | Aug 8, 2022
Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.
old dog smiles at camera
Inside the Brains of Aging Dogs
Lesley Evans Ogden, Knowable Magazine | Aug 1, 2022
In a citizen science project, thousands of pet dogs are helping scientists to understand what happens to memory and cognition in old age.
Infographic showing how neurodegenerative diseases have long been associated with aggregations of apparently toxic proteins
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Catherine Offord | Aug 1, 2022
Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.
The balance of mind and body on a seesaw
Psychological Stress Distracts the Immune System from Fighting Infections
Jennifer Zieba, PhD | Aug 8, 2022
Acute stress makes immune cells migrate immediately to the bone marrow, which prepares the body for injury at the expense of increasing infectious disease susceptibility.
Amyloid plaques on axons of neurons
The Misunderstood Proteins of Neurodegeneration
Catherine Offord | Aug 1, 2022
The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the development of disease.
A dolphin comes out of the water to catch a red ball.<br><br>
Dolphins May Remember Personal Experiences
Alejandra Manjarrez | Jul 29, 2022
Bottlenose dolphins can recall trivial details of a prior event to later solve a novel task, a study finds, suggesting these mammals are capable of episodic memory.
A Rising Star Launches Brain Power into Outer Space
Science Philosophy in a Flash - A Rising Star Launches Brain Power into Outer Space
Iris Kulbatski, PhD | Jul 27, 2022
Alysson Muotri shares how tapping into his inner creative spark fuels his pursuit of science.
Calm lake reflecting sky with boat in foreground
Plastic Pollution Boosts Bacterial Growth in Lake Water
Patience Asanga | Jul 26, 2022
A study finds that not only did aquatic bacteria thrive when chemicals washed from degrading plastic were introduced into lake water, they also broke down organic matter more efficiently.
Fluorescent cells in culture connected by tunneling nanotubules
SARS-CoV-2 Could Use Nanotubes to Infect the Brain
Natalia Mesa | Jul 21, 2022
Stressed cells can form hollow actin bridges to neighbors to get help, but the virus may hijack these tiny tunnels for its own purposes, a study suggests.
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Fortis Life Sciences | Jun 20, 2022
Identifying novel biomarkers of Parkinson’s disease enables early diagnosis and treatment monitoring.
Illustration of brain activity
Same Parts of the Brain Control Processing of Dozens of Languages
Andy Carstens | Jul 21, 2022
While much is known about how the brains of English speakers process language, research has neglected people who speak other languages. The Scientist spoke with one of the authors of a study that seeks to change that.
illustration of brain with DNA strand coming out the top
Genetic Underpinnings of Brain Activity May Differ in Autism
Emily Harris | Jul 19, 2022
A study finds that expression levels of certain genes that track with brain activity—particularly those involved in brain development—vary between people with autism and their non-autistic peers.
The Mosaic Brain
Sejal Davla, PhD | Jun 1, 2022
How somatic mutations cause brain diseases
gray mouse drinking from water bottle in cage
“Feel-Good” Neurons Steer Mice Toward Hydration-Boosting Liquids
Shafaq Zia | Jul 19, 2022
The cells signal to the brain how hydrating particular beverages are, but it’s not yet clear whether they play a similar role in humans.