Baby face up in spotted onesie about to get an injection with a vaccine
Antibiotics Tied to Lower Effectiveness of Childhood Vaccines
Use of the drugs in children under the age of two was associated with lower antibody levels after the jabs—perhaps, researchers suggest, due to microbiome alterations.
ABOVE: © iStock.com, Daniel Balakov
Antibiotics Tied to Lower Effectiveness of Childhood Vaccines
Antibiotics Tied to Lower Effectiveness of Childhood Vaccines

Use of the drugs in children under the age of two was associated with lower antibody levels after the jabs—perhaps, researchers suggest, due to microbiome alterations.

Use of the drugs in children under the age of two was associated with lower antibody levels after the jabs—perhaps, researchers suggest, due to microbiome alterations.

ABOVE: © iStock.com, Daniel Balakov

polio

Child with head tilted back receiving oral polio vaccine
Mass Polio Vaccination Effort Underway in East Africa
Natalia Mesa | Mar 18, 2022
Malawi and its neighbors plan to vaccinate 9.4 million children against polio in the coming week to combat a suspected outbreak.
How Some Vaccines Protect Against More than Their Targets
Shawna Williams | Nov 1, 2020
As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.
Treatment Against All Odds
The Scientist Staff | Jul 13, 2020
Jean Macnamara, a pioneer in the treatment of polio patients and the subject of this issue’s Foundations, comes to life in the form of a Google Doodle to celebrate what would have been her 121st birthday.
Jean Macnamara’s Multiple Causes, 1931
Catherine Offord | Jul 13, 2020
The medical scientist made important contributions to polio treatment and Australian environmental policy—despite substantial resistance.
poliovirus nprv2 vaccine-derived polio reversion virulence 481a mutation genetic engineering
New Oral Polio Vaccine to Bypass Key Clinical Trials
Robert Fortner | Dec 17, 2019
Health officials are rushing a genetically engineered product into the field to counter uncontained outbreaks of vaccine-derived polio.
Polio Vaccination Causes More Infections than Wild Virus
Jef Akst | Nov 25, 2019
In rare instances, the live virus in oral polio vaccines can mutate and become infectious, causing new outbreaks.
More Evidence that Enterovirus May Cause Kids’ Paralyzing Disease
Catherine Offord | Oct 22, 2019
Children with acute flaccid myelitis are more likely to have antibodies against the viral family in their spinal fluid than are children without the illness.
Enterovirus Might Be Behind Kids’ Paralysis: Preprint
Catherine Offord | Jun 17, 2019
Researchers identify a possible driver of acute flaccid myelitis, a polio-like disease diagnosed in more than 500 children over the last few years.
More Reports of Children Being Paralyzed by Mysterious Disease
Ashley P. Taylor | Oct 17, 2018
Dozens of cases of acute flaccid myelitis have occurred this year, and while it resembles polio, health officials have ruled out poliovirus.
Polio Vaccine Pioneer Dies
Kerry Grens | May 2, 2017
Julius Youngner collaborated with Jonas Salk on the polio vaccine, and later identified interferon gamma and contributed to an equine influenza vaccine.
Pathway to Polio Virulence Revealed
Ashley P. Taylor | Mar 23, 2017
Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.
Toward a Virus-Free Polio Vaccine
Ashley P. Taylor | Jan 19, 2017
Researchers are developing polio vaccines based on the viral capsid alone. When produced in recombinant systems, these could eliminate the need to propagate live poliovirus for vaccine production. 
Polio Reemerges in Nigeria
Jef Akst | Aug 15, 2016
Prior to last week’s announcement of newly confirmed cases, the country had been polio-free for two years.
Speaking of Microbiology
Tanya Lewis and Tracy Vence | Jun 21, 2016
A selection of notable quotes from the American Society for Microbiology’s annual meeting
Updating the Polio Vaccine
Jef Akst | Jan 4, 2016
Researchers develop new attenuated viruses that could support the eradication effort.
Toward Eliminating Poliovirus—In the Lab
Rina Shaikh-Lesko | Nov 16, 2015
As the world inches closer to polio eradication, laboratories studying the virus will have to bolster biosafety standards. Eventually, most will need to stop working with the pathogen entirely.
Polio No Longer Endemic in Nigeria
Tracy Vence | Sep 29, 2015
It’s been more than a year since the country has reported a case of wild poliovirus, according to the World Health Organization. 
Driven to Extinction
Jef Akst | Jul 1, 2015
The eradication of smallpox set the standard for the global elimination of a devastating infectious disease. Will the ongoing polio and guinea worm campaigns be as successful?
The Year in Pathogens
Molly Sharlach | Dec 28, 2014
Ebola, MERS, and enterovirus D68; polio eradication efforts; new regulations on potentially dangerous research