How Some Vaccines Protect Against More than Their Targets
How Some Vaccines Protect Against More than Their Targets
As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.
How Some Vaccines Protect Against More than Their Targets
How Some Vaccines Protect Against More than Their Targets

As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.

As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.

polio
Treatment Against All Odds
Treatment Against All Odds
The Scientist Staff | Jul 13, 2020
Jean Macnamara, a pioneer in the treatment of polio patients and the subject of this issue’s Foundations, comes to life in the form of a Google Doodle to celebrate what would have been her 121st birthday.
Jean Macnamara’s Multiple Causes, 1931
Jean Macnamara’s Multiple Causes, 1931
Catherine Offord | Jul 13, 2020
The medical scientist made important contributions to polio treatment and Australian environmental policy—despite substantial resistance.
New Oral Polio Vaccine to Bypass Key Clinical Trials
New Oral Polio Vaccine to Bypass Key Clinical Trials
Robert Fortner | Dec 17, 2019
Health officials are rushing a genetically engineered product into the field to counter uncontained outbreaks of vaccine-derived polio.
Polio Vaccination Causes More Infections than Wild Virus
Polio Vaccination Causes More Infections than Wild Virus
Jef Akst | Nov 25, 2019
In rare instances, the live virus in oral polio vaccines can mutate and become infectious, causing new outbreaks.
More Evidence that Enterovirus May Cause Kids’ Paralyzing Disease
More Evidence that Enterovirus May Cause Kids’ Paralyzing Disease
Catherine Offord | Oct 22, 2019
Children with acute flaccid myelitis are more likely to have antibodies against the viral family in their spinal fluid than are children without the illness.
Enterovirus Might Be Behind Kids’ Paralysis: Preprint
Enterovirus Might Be Behind Kids’ Paralysis: Preprint
Catherine Offord | Jun 17, 2019
Researchers identify a possible driver of acute flaccid myelitis, a polio-like disease diagnosed in more than 500 children over the last few years.
More Reports of Children Being Paralyzed by Mysterious Disease
More Reports of Children Being Paralyzed by Mysterious Disease
Ashley P. Taylor | Oct 17, 2018
Dozens of cases of acute flaccid myelitis have occurred this year, and while it resembles polio, health officials have ruled out poliovirus.
Polio Vaccine Pioneer Dies
Polio Vaccine Pioneer Dies
Kerry Grens | May 2, 2017
Julius Youngner collaborated with Jonas Salk on the polio vaccine, and later identified interferon gamma and contributed to an equine influenza vaccine.
Pathway to Polio Virulence Revealed
Pathway to Polio Virulence Revealed
Ashley P. Taylor | Mar 23, 2017
Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.
Toward a Virus-Free Polio Vaccine
Toward a Virus-Free Polio Vaccine
Ashley P. Taylor | Jan 19, 2017
Researchers are developing polio vaccines based on the viral capsid alone. When produced in recombinant systems, these could eliminate the need to propagate live poliovirus for vaccine production. 
Polio Reemerges in Nigeria
Polio Reemerges in Nigeria
Jef Akst | Aug 15, 2016
Prior to last week’s announcement of newly confirmed cases, the country had been polio-free for two years.
Speaking of Microbiology
Speaking of Microbiology
Tanya Lewis and Tracy Vence | Jun 21, 2016
A selection of notable quotes from the American Society for Microbiology’s annual meeting
Updating the Polio Vaccine
Updating the Polio Vaccine
Jef Akst | Jan 4, 2016
Researchers develop new attenuated viruses that could support the eradication effort.
Toward Eliminating Poliovirus—In the Lab
Toward Eliminating Poliovirus—In the Lab
Rina Shaikh-Lesko | Nov 16, 2015
As the world inches closer to polio eradication, laboratories studying the virus will have to bolster biosafety standards. Eventually, most will need to stop working with the pathogen entirely.
Polio No Longer Endemic in Nigeria
Polio No Longer Endemic in Nigeria
Tracy Vence | Sep 29, 2015
It’s been more than a year since the country has reported a case of wild poliovirus, according to the World Health Organization. 
Driven to Extinction
Driven to Extinction
Jef Akst | Jul 1, 2015
The eradication of smallpox set the standard for the global elimination of a devastating infectious disease. Will the ongoing polio and guinea worm campaigns be as successful?
The Year in Pathogens
The Year in Pathogens
Molly Sharlach | Dec 28, 2014
Ebola, MERS, and enterovirus D68; polio eradication efforts; new regulations on potentially dangerous research
Polio Spreads in Pakistan
Polio Spreads in Pakistan
Kerry Grens | Oct 8, 2014
So far this year, 200 Pakistanis have been diagnosed with polio, the most in more than a decade.