Self-Experimentation in the Time of COVID-19
Self-Experimentation in the Time of COVID-19
Scientists are taking their own vaccines, an ethically murky practice that has a long and sometimes celebrated history in medicine.
Self-Experimentation in the Time of COVID-19
Self-Experimentation in the Time of COVID-19

Scientists are taking their own vaccines, an ethically murky practice that has a long and sometimes celebrated history in medicine.

Scientists are taking their own vaccines, an ethically murky practice that has a long and sometimes celebrated history in medicine.

poliovirus
Jean Macnamara’s Multiple Causes, 1931
Jean Macnamara’s Multiple Causes, 1931
Catherine Offord | Jul 13, 2020
The medical scientist made important contributions to polio treatment and Australian environmental policy—despite substantial resistance.
New Oral Polio Vaccine to Bypass Key Clinical Trials
New Oral Polio Vaccine to Bypass Key Clinical Trials
Robert Fortner | Dec 17, 2019
Health officials are rushing a genetically engineered product into the field to counter uncontained outbreaks of vaccine-derived polio.
Polio Vaccination Causes More Infections than Wild Virus
Polio Vaccination Causes More Infections than Wild Virus
Jef Akst | Nov 25, 2019
In rare instances, the live virus in oral polio vaccines can mutate and become infectious, causing new outbreaks.
More Evidence that Enterovirus May Cause Kids’ Paralyzing Disease
More Evidence that Enterovirus May Cause Kids’ Paralyzing Disease
Catherine Offord | Oct 22, 2019
Children with acute flaccid myelitis are more likely to have antibodies against the viral family in their spinal fluid than are children without the illness.
Enterovirus Might Be Behind Kids’ Paralysis: Preprint
Enterovirus Might Be Behind Kids’ Paralysis: Preprint
Catherine Offord | Jun 17, 2019
Researchers identify a possible driver of acute flaccid myelitis, a polio-like disease diagnosed in more than 500 children over the last few years.
Poliovirus Therapy May Extend Lives of Advanced Brain-Cancer Patients
Poliovirus Therapy May Extend Lives of Advanced Brain-Cancer Patients
Ashley Yeager | Jun 26, 2018
More than one-fifth of individuals treated with the genetically modified virus survived at least three years.
Pathway to Polio Virulence Revealed
Pathway to Polio Virulence Revealed
Ashley P. Taylor | Mar 23, 2017
Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.
Toward a Virus-Free Polio Vaccine
Toward a Virus-Free Polio Vaccine
Ashley P. Taylor | Jan 19, 2017
Researchers are developing polio vaccines based on the viral capsid alone. When produced in recombinant systems, these could eliminate the need to propagate live poliovirus for vaccine production. 
Polio Reemerges in Nigeria
Polio Reemerges in Nigeria
Jef Akst | Aug 15, 2016
Prior to last week’s announcement of newly confirmed cases, the country had been polio-free for two years.