protein engineering, cell & molecular biology
Extra DNA Base Discovered
Extra DNA Base Discovered
Jef Akst | Jun 23, 2015
An epigenetic variant of cytosine is stable in the genomes of living mice, suggesting a possible expansion of the DNA alphabet.
The Handedness of Cells
The Handedness of Cells
Kerry Grens | Jun 17, 2015
Actin—the bones of the cell—has a preference for swirling into a counterclockwise pattern.
Prominent Cell Biologist Dies
Prominent Cell Biologist Dies
Kerry Grens | May 4, 2015
Cytoskeleton specialist Alan Hall was best known for unpacking the roles of Rho GTPases.   
Cellular Garbage Disposal Illuminated
Cellular Garbage Disposal Illuminated
Bob Grant | Apr 13, 2015
A Harvard team shows how cells label and recognize proteins for degradation.
2015 Top 10 Innovations: Enter Today!
2015 Top 10 Innovations: Enter Today!
The Scientist | Apr 13, 2015
Submissions are officially open for this year’s Top 10 Innovations contest.
A Benefit of Failed Pregnancy?
A Benefit of Failed Pregnancy?
Ruth Williams | Apr 9, 2015
Scientists find a common genetic variant in mothers that decreases the chance of successful pregnancy.
Yvonne Saenger: Immunotherapy Pioneer
Yvonne Saenger: Immunotherapy Pioneer
Jef Akst | Apr 1, 2015
Assistant Professor, Department of Medicine, Columbia University. Age: 41
Signaling Resistance
Signaling Resistance
Jenny Rood | Apr 1, 2015
Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.
Toggling Between Life and Death
Toggling Between Life and Death
Ashley P. Taylor | Apr 1, 2015
In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.
Setbacks and Great Leaps
Setbacks and Great Leaps
Sue Armstrong | Apr 1, 2015
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.