Illustration of light blue neurons with white amyloid plaques accumulating on their axons.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial

The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.

The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.

protozoans, disease & medicine, neuroscience, cell & molecular biology
white mouse sitting down
Drug Spurs Neuron Growth in Mice with Chronic Spinal Cord Injury
Natalia Mesa | Sep 27, 2022
A protein duo increases transcription of growth-related genes to enhance axon regeneration and boost plasticity, a study finds—but fails to improve mobility.
pregnant belly clad in hospital gown with IV line going into hand
Registry Review Casts Doubt on Causal Link Between Maternal Infection and Autism
Charles Q. Choi, Spectrum | Sep 26, 2022
Maternal infection during pregnancy may be associated with autism, as previous studies have suggested—but perhaps not in a causal way.
Capturing Brain Complexity in Assembloids
Capturing Brain Complexity in Assembloids
The Scientist Creative Services Team
In this webinar, Jimena Anderson and Jens Schwamborn will describe the next-generation brain organoids that combine multiple brain regions and cell types in 3D cultures.
A mouse brain showing activated neurons (white) in the brainstem 3 hours after LPS injection.
Research Pinpoints the Neurons Behind Feeling Sick
James M. Gaines | Sep 23, 2022
Specific neurons in the brainstem control sickness behaviors not directly caused by a pathogen, such as tiredness and lack of appetite, a mouse study finds.
A ball-and-stick plus ribbons molecular model of the hormone orexin, also known as hypocretin, isolated on a white background.
2023 Breakthrough Prizes Showcase Research in AI and Narcolepsy
Amanda Heidt | Sep 22, 2022
Three prizes were awarded to six researchers working across the life sciences on cellular organization, protein structure, and the genetic underpinnings of a chronic sleep disorder.
Neurons traversing the brain with an area of red neurodegeneration
LabTalk Podcast - The New Era of Neurodegeneration Research
The Scientist Creative Services Team
Erdem Gültekin Tamgüney discusses the future of neurodegeneration research and his work exploring the link between stroke and Parkinson’s disease.
Woman holding a glass of water in one hand and pill in the other
Daily Multivitamin May Slow Cognitive Decline in Seniors
Andy Carstens | Sep 14, 2022
Researchers caution that it’s too soon to recommend supplements based on the results of a new study.
artistic representation of jumping gene
Jumping Genes Can Cause Movement Disorder: Study
Sophie Fessl | Sep 13, 2022
Mice with overactive LINE-1 retrotransposons in their brains exhibit movement difficulties, suggesting the genetic elements may play a role in ataxia in humans. 
Time Traveling Mini-Brains on a Mission to Conquer Space
Time Traveling Mini-Brains on a Mission to Conquer Space
Iris Kulbatski, PhD
Alysson R. Muotri discusses his launch of brain organoids into outer space and how microgravity enriches our understanding of brain development and disease.
Newborn baby rats lie in a basket
Mother’s Circadian Rhythms Mirrored in Fetal Rat Brains
Bianca Nogrady | Sep 12, 2022
Before their own central clocks develop, the brains of fetal rats detect their mother’s metabolic cycle to help regulate the expression of certain genes.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox | Sep 12, 2022
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Motor neurons, undergoing degeneration in ALS
Mutant T Cells That Drive Amyotrophic Lateral Sclerosis (ALS) Progression May React To a Brain Antigen
Nele Haelterman, PhD
Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.
Genetic knockout experiments reveal a role for the protein in forming and maintaining synapses between motor neurons and muscle fibers in mice.
Infographic: Vangl2 in Muscles Keeps Neuromuscular Junctions Organized
Catherine Offord | Sep 12, 2022
Genetic knockout experiments reveal a role for the protein in forming and maintaining synapses between motor neurons and muscle fibers in mice.
Neurons and muscle tissue
A Novel Player at the Neuromuscular Junction
Catherine Offord | Sep 12, 2022
The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes.
The balance of mind and body on a seesaw
Psychological Stress Distracts the Immune System from Fighting Infections
Jennifer Zieba, PhD
Acute stress makes immune cells migrate immediately to the bone marrow, which prepares the body for injury at the expense of increasing infectious disease susceptibility.
Illustration of RNAs
Infographic: Noncoding RNA in the Brain
Christie Wilcox | Sep 12, 2022
Neurologically important noncoding RNAs come in many shapes and sizes.
Illustration of a human and Neanderthal skull side by side.
Mutation Linked to Difference Between Human and Neanderthal Brains
Dan Robitzski | Sep 9, 2022
A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
The Scientist Creative Services Team and PerkinElmer
Robin Ketteler and Hélène Plun-Favreau discuss the importance of autophagy and mitophagy regulation in neurodegenerative diseases.
Adipose tissue under the microscope appearing as red blobs on a white background
Mouse Brains Appear to Eavesdrop on Their Fat
Alejandra Manjarrez | Sep 9, 2022
For the first time, a team visualizes sensory nerves projecting into adipose tissue in mice and finds these neuronal cells may counteract the local effects of the sympathetic nervous system.