rare diseases, developmental biology, immunology, cell & molecular biology
Image of the Day: Nanobot Schematic
Image of the Day: Nanobot Schematic
The Scientist Staff | Apr 13, 2018
A magnetically controlled device could have applications in studies of cell biology and biophysics.
New Ovarian Cancer Vaccine Shows Promise
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Some Antibiotics Rev Up Host Immune Response to Viruses
Some Antibiotics Rev Up Host Immune Response to Viruses
Shawna Williams | Apr 9, 2018
The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.
Opinion: We Have Been Naive About Naive T Cells
Opinion: We Have Been Naive About Naive T Cells
Jos├ę A.M. Borghans, Femke van Wijk, Theo van den Broek | Apr 6, 2018
Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.
Ruth Nussenzweig, Malaria Researcher, Dies
Ruth Nussenzweig, Malaria Researcher, Dies
Jim Daley | Apr 5, 2018
The microbiologist’s research led to the development of the first human malaria vaccine.
Image of the Day: Cell Droplets
Image of the Day: Cell Droplets
The Scientist Staff | Apr 4, 2018
Proteins and RNA aggregate into “membraneless organelles” due to liquid-liquid phase separation.
Chromosomal Instability Drives Cancer Metastasis
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Jim Daley | Apr 1, 2018
Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.
Perineuronal Nets: A Mechanism to Control Brain Plasticity
Perineuronal Nets: A Mechanism to Control Brain Plasticity
Daniela Carulli | Apr 1, 2018
The neuronal coverings that mediate synaptic changes are involved in everything from memory to psychiatric disorders, affecting autism, Alzheimer’s, and addiction.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018
Errors in segregation during cell division can lead to inflammation in daughter cells.