research misconduct, cell & molecular biology
Short, Strong Signals
Ruth Williams | Mar 25, 2015
Methylation increases both the activity and instability of the signaling protein Notch.
Irisin Skepticism Goes Way Back
Kerry Grens | Mar 18, 2015
Post-publication peer reviewers had questioned data about the supposed fat-browning enzyme from the get-go.
On the Origins of Life
Jef Akst | Mar 17, 2015
A new experimental system demonstrates that precursors of ribonucleotides, amino acids, and lipids may have simultaneously arisen from the same prebiotic chemistry.
Long Live Collagen
Ashley P. Taylor | Mar 1, 2015
Increased collagen expression is a common feature of many different pathways to extended longevity in worms.
Growth Hormone Guidance
Jenny Rood | Mar 1, 2015
Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.
Weiwei Dang: Epigenetics in Aging
Jef Akst | Mar 1, 2015
Assistant Professor, Huffington Center On Aging, Baylor College of Medicine. Age: 38
HIV Scientist Pleads Guilty to Fraud
Bob Grant | Feb 26, 2015
A former Iowa State University researcher faces up to 10 years in prison for faking data involving a study of an HIV vaccine.
Evolutionary Rewiring
Ruth Williams | Feb 26, 2015
Strong selective pressure can lead to rapid and reproducible evolution in bacteria.
Stem Cells Phone Home
Jef Akst | Feb 26, 2015
A screen of 9,000 small molecules identifies a treatment that improves the targeting of mesenchymal stem cells to sites of damaged tissue.
The Dark Side of Melanin
Anna Azvolinsky | Feb 19, 2015
Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.
Signs of Sleep Deprivation in the Blood
Bob Grant | Feb 11, 2015
Circulating fats and acids drop in people and rats that aren’t getting enough sleep.
Crystal Structure, Murky Function
Ruth Williams | Jan 29, 2015
Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.
Interferon Discoverer Dies
Kerry Grens | Jan 26, 2015
Jean Lindemann, the virologist who helped figure out that interferons were responsible for anti-viral responses, has passed away at age 90.
Human Proteome Mapped Again
Anna Azvolinsky | Jan 22, 2015
Researchers complete another interactive protein atlas, boosting the number of publicly available maps of human protein expression levels.
Mitochondrial Enzyme Detailed
Jef Akst | Jan 9, 2015
Researchers reveal clues regarding how an ancient mitochondrial enzyme helps maintain healthy cells across the tree of life.
Stress Fractures
Daniel Cossins | Jan 1, 2015
Social adversity shapes humans’ immune systems—and probably their susceptibility to disease—by altering the expression of large groups of genes.
Top Science Scandals of 2014
Jef Akst | Dec 24, 2014
The stem cell that never was; post-publication peer review website faces legal trouble; biosecurity breaches at federal labs
Reprogramming Redux
Anna Azvolinsky | Dec 18, 2014
Can mechanical forces alone be manipulated to create stem-like cells?
Honeybee Compound for Hair Loss?
Jef Akst | Dec 11, 2014
Propolis, a natural product used by honeybees to repair their hives, stimulates hair growth in shaved mice.
New Ruling on Old Misconduct Case
Jef Akst | Dec 10, 2014
The Office of Research Integrity has finally pointed the finger in a case of suspected data manipulation in a 2006 Science paper.