retraction, ecology, cell & molecular biology
Control ALT, Delete Cancer
Control ALT, Delete Cancer
Haroldo Silva, David Halvorsen, Jeremy D. Henson | Apr 1, 2015
Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway
Cancer Kismet
Cancer Kismet
Jenny Rood | Apr 1, 2015
Fate mapping allows researchers to follow cancer progression from its cell type of origin.
Cancer Immunotherapist
Cancer Immunotherapist
Jef Akst | Apr 1, 2015
Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.
Book Excerpt from <em>p53</em>
Book Excerpt from p53
Sue Armstrong | Apr 1, 2015
In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.
Resisting Cancer
Resisting Cancer
George Klein | Apr 1, 2015
If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.
From Many, One
From Many, One
Elena E. Giorgi | Apr 1, 2015
Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?
Mass Retraction
Mass Retraction
Bob Grant | Mar 27, 2015
BioMed Central retracts 43 papers it had been investigating for evidence of faked peer review.
Short, Strong Signals
Short, Strong Signals
Ruth Williams | Mar 25, 2015
Methylation increases both the activity and instability of the signaling protein Notch.
Three Retractions for Highly Cited Author
Three Retractions for Highly Cited Author
Kerry Grens | Mar 19, 2015
Robert Weinberg’s team at MIT is pulling three papers, noting some figure panels were composites of different experiments.
Irisin Skepticism Goes Way Back
Irisin Skepticism Goes Way Back
Kerry Grens | Mar 18, 2015
Post-publication peer reviewers had questioned data about the supposed fat-browning enzyme from the get-go.