somatic mutations, disease & medicine
Stem Cell Divisions Help Explain Cancer Risk
Stem Cell Divisions Help Explain Cancer Risk
Anna Azvolinsky | Jan 1, 2015
An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk.  
Experimental Ebola Drug Shows Promise
Experimental Ebola Drug Shows Promise
Tracy Vence | Sep 2, 2014
ZMapp effectively rescued macaques from Ebola in a small trial, but it could be several months before supplies of the drug meet the growing human demand for it.
WHO OKs Experimental Ebola Drugs
WHO OKs Experimental Ebola Drugs
Tracy Vence | Aug 13, 2014
But biotech firms’ supplies are dwindling.
Mosaic Mutations
Mosaic Mutations
Kate Yandell | Jul 31, 2014
Some genetic abnormalities that appear to have sprung up independently in children are in fact present in a portion of their parents’ cells.
Genetic Test Could Replace Pap Smear
Genetic Test Could Replace Pap Smear
Kerry Grens | Apr 25, 2014
The US Food and Drug Administration approves a cervical test for human papillomavirus to be used as a primary cancer screening tool.
Elder Pharmacology
Elder Pharmacology
Nir Barzilai | Jan 1, 2014
Studying and treating the chronic diseases associated with aging needs serious revamping.
Mutation Patterns Underlie Cancers
Mutation Patterns Underlie Cancers
Kerry Grens | Aug 15, 2013
More than 20 genome-wide mutational “signatures” account for the vast majority of 30 common cancers.
New Type of DNA Discovered?
Sabrina Richards | Mar 8, 2012
Small circles of extrachromosomal DNA appear to be widespread in mammals, and may be byproducts of small deletions in the nuclear DNA of somatic cells.
Deconstructing the Mosaic Brain
Tom Curran | Aug 1, 2011
Sequencing the DNA of individual neurons is a way to dissect the genes underlying major neurological and psychological disorders.