Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

stem cell trials, cell & molecular biology
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
The Role of Mom’s Microbes During Pregnancy
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson, Kathy D. McCoy | Aug 1, 2021
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Predictions of Most Human Protein Structures Made Freely Available
Predictions of Most Human Protein Structures Made Freely Available
Lisa Winter | Jul 23, 2021
The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms.
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Sophie Fessl | Jul 16, 2021
Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.
Human Protein Dissolves Bacterial Membranes
Human Protein Dissolves Bacterial Membranes
Abby Olena | Jul 15, 2021
The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.
Q&A: Eating Milk Chocolate in the Morning Boosts Fat Metabolism
Q&A: Eating Milk Chocolate in the Morning Boosts Fat Metabolism
Amanda Heidt | Jun 30, 2021
A study of 19 postmenopausal women found that eating a bar of chocolate in the morning affected their bodies differently than eating it at night, but neither led to weight gain.
What’s the Deal with Bacterial Nanotubes?
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
Blind Patient Recovers Partial Vision with Optogenetics
Blind Patient Recovers Partial Vision with Optogenetics
Alejandra Manjarrez | May 24, 2021
After receiving an intraocular injection of the gene for a light-sensitive protein, a 58-year-old man diagnosed with the neurodegenerative eye disease retinitis pigmentosa was able to locate objects on a table using engineered goggles.
Coronavirus Mutations Could Muddle COVID-19 PCR Tests
Coronavirus Mutations Could Muddle COVID-19 PCR Tests
Jack J. Lee | May 17, 2021
Researchers find that SARS-CoV-2 variants can evade primer-probe sets and recommend that diagnostic assays include multiple targets for reliability.
Comprehensive Atlas of Reef-Building Coral’s Cells Created
Comprehensive Atlas of Reef-Building Coral’s Cells Created
Christie Wilcox | May 13, 2021
Single-cell RNA sequencing helps to catalog the dozens of cell types present in a stony coral, including its elusive immune cells.
When Severed, This Solitary Tunicate Regrows as Three New Animals
When Severed, This Solitary Tunicate Regrows as Three New Animals
Amanda Heidt | May 13, 2021
While regeneration has long been the domain of colonial tunicates, a solitary species of sea squirt was able to regenerate into multiple, fully functional individuals within a month of being cut up.
Cancer Cells Parasitize Other Ones to Survive: Study
Cancer Cells Parasitize Other Ones to Survive: Study
Marcus A. Banks | May 13, 2021
Tumor cells missing a critical protein enter neighboring cells to sap their nutrients, then exit those hosts as intact cells, possibly primed to metastasize. Other scholars say it’s too early to know this for sure.