stem cells, developmental biology, microbiology
CRISPRi-Controlled Gene Expression
CRISPRi-Controlled Gene Expression
Jef Akst | Mar 10, 2016
A variation of the gene-editing technique can more precisely and efficiently downregulate the expression of target genes than traditional CRISPR/Cas9.
Surgery, Stem Cells Treat Cataracts
Surgery, Stem Cells Treat Cataracts
Catherine Offord | Mar 10, 2016
A surgical technique that removes the lens but leaves endogenous stem cells to allow lens regrowth shows promise in animal and early human trials.
Opinion: A Mother’s Microbes
Opinion: A Mother’s Microbes
Rob Knight and Jack Gilbert | Mar 3, 2016
On “vaginal seeding” and the challenge of evidence-based parenting
Amoebae Have Human-Like Immunity
Amoebae Have Human-Like Immunity
Jef Akst | Mar 2, 2016
Dictyostelium discoideum produce extracellular nets that can kill bacteria, just as phagocytes in people and other higher animals do, according to a study.
Giant Virus Has CRISPR-like Immune Defense
Giant Virus Has CRISPR-like Immune Defense
Kerry Grens | Mar 2, 2016
The genome of a mimivirus strain resistant to a virophage has repeated phage sequences alongside nuclease- and helicase-coding sections.
Spoiler Alert
Spoiler Alert
Wudan Yan | Mar 1, 2016
How to store microbiome samples without losing or altering diversity
Week in Review: February 22–26
Week in Review: February 22–26
Jef Akst | Feb 26, 2016
Questions about how E. coli evolves; spermatids in a dish; fighting bacteria with virus-like molecule; what drives metastasis; antibodies fight Ebola in monkeys
Toward Making Sperm in the Lab
Toward Making Sperm in the Lab
Rina Shaikh-Lesko | Feb 25, 2016
Researchers devise a technique for creating gametes from murine embryonic stem cells.
iPSCs and Cancer Risk
iPSCs and Cancer Risk
Catherine Offord | Feb 24, 2016
Reprogramming adult human cells into stem cells in vitro does not generate harmful mutations, scientists report.
Similar Data, Different Conclusions
Similar Data, Different Conclusions
Ashley P. Taylor | Feb 23, 2016
By tweaking certain conditions of a long-running experiment on E. coli, scientists found that some bacteria could be prompted to express a mutant phenotype sooner, without the “generation of new genetic information.” The resulting debate—whether the data support evolutionary theory—is more about semantics than science.