A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more effective antibody production against HIV in rhesus monkeys, a study finds.
Slow Vaccine Delivery May Maximize Immune Response
Slow Vaccine Delivery May Maximize Immune Response

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more effective antibody production against HIV in rhesus monkeys, a study finds.

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more effective antibody production against HIV in rhesus monkeys, a study finds.

structural biology, disease & medicine, immunology
People in protective gear enter a building during an Ebola simulation exercise in Uganda in 2019. 
Uganda Declares Ebola Outbreak After Fatality
Katherine Irving | Sep 20, 2022
The outbreak of the Sudan strain of ebolavirus, which includes eight other suspected cases, is the first to hit Uganda in more than a decade.
3D rendered images of three T cell
T Cells Ward Off Aging with Help from Their Friends
Natalia Mesa | Sep 16, 2022
Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.
Exploring the SARS-CoV-2 Outer Cell Surface
Exploring the SARS-CoV-2 Outer Cell Surface: Lessons in Innate and Adaptive Immunity
The Scientist Creative Services Team
In this webinar, Alberto Lopez-Munoz will discuss SARS-CoV-2 nucleocapsid protein cell surface expression and its role in host immunity.
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez | Sep 15, 2022
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
A surgical mask next to an open pill bottle that&rsquo;s toppled over, spilling out red capsules meant to represent vitamin D supplements.
Vitamin D Likely Doesn’t Prevent COVID-19, Studies Find
Dan Robitzski | Sep 9, 2022
The results from two large clinical trials don't support the idea that supplements of the vitamin bolster immune defenses against SARS-CoV-2.
Ancient Mummies&rsquo; Lousy View of the Past
Ancient Mummies’ Lousy View of the Past
Nele Haelterman, PhD
Researchers develop method to study ancient human DNA preserved by head lice.
Bright purple and orange lactobacillus bacteria.
How a Specific Gut Bacterium May Cause Type 1 Diabetes
Dan Robitzski | Aug 25, 2022
A bacterium that produces an insulin-like peptide can give mice type 1 diabetes, and infection with the microbe seems to predict the onset of the disease in humans, a study finds.
Illustration of a red bacteriophage infecting a blue bacterium, with other bacteria in the background.
Prokaryotes Are Capable of Learning to Recognize Phages
Patience Asanga | Aug 17, 2022
Immune defense genes in bacteria and archaea can identify viral proteins, a study finds, revealing similarities between the immune systems of prokaryotic and eukaryotic organisms.
Small Changes, Big Consequences
Small Changes, Big Consequences
Niki Spahich, PhD
To understand the mechanisms behind severe COVID-19, researchers identified common COVID-19 genetic risk variants that affect immune cell function.
An illustration of a pregnant women wearing a mask, surrounded by microbes
How COVID-19 Affects Pregnancy
Amanda Heidt | Aug 16, 2022
Evidence thus far shows that pregnant people infected with SARS-CoV-2 are at higher risk for severe disease and death, as well as complications in their pregnancies.
Artist’s rendition of light blue monkeypox viruses in front of a black background.
FDA To Stretch Monkeypox Vaccine Supply via Intradermal Injection
Shafaq Zia | Aug 12, 2022
The newly authorized intradermal vaccination only requires one-fifth of the usual vaccine dose. This will help stretch out the limited vaccine supply, experts say, but only if healthcare personnel receive sufficient training.
Uncovering Leprosy&rsquo;s Genetic Recipe for Success
Uncovering Leprosy’s Genetic Recipe for Success
Nele Haelterman, PhD
Researchers identify what makes certain people more likely to contract leprosy than others.
Man in lab coat looking at the camera and smiling
Can Taking a Test Now Tell You if You’ve Already Had COVID-19?
Natalia Mesa | Aug 8, 2022
The Scientist asks Brigham and Women’s Hospital infectious disease specialist Lindsey Baden about testing for prior infections.
Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Holly Barker | Aug 5, 2022
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
GENETIC PREDISPOSITION TO VITAMIN D DEFICIENCY CONTRIBUTES TO SEVERE COVID-19
Genetic Predisposition to Vitamin D Deficiency Contributes to Severe COVID-19
Iris Kulbatski, PhD
Ana Teresa Freitas discusses how individual variation in vitamin D synthesis and metabolism influences susceptibility to upper respiratory viruses.
Photo of Makio Murayama
Handmade Hemoglobin, 1912-2012
Dan Robitzski | Aug 1, 2022
Makio Murayama, a Japanese-American biochemist who was turned away from the Manhattan Project due to his heritage, rose to prominence for his work uncovering the link between the structure of hemoglobin and the mechanisms of sickle cell disease.
Infographic showing how neurodegenerative diseases have long been associated with aggregations of apparently toxic proteins
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Catherine Offord | Aug 1, 2022
Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.
A New Multiplexed SARS-CoV-2 Serological Assay Using Advanced Flow Cytometry
A New Multiplexed SARS-CoV-2 Serological Assay Using Advanced Flow Cytometry
The Scientist Creative Services Team
Julie Lovchik will discuss how advanced flow cytometry instrumentation facilitates multiplex assessment of IgG, IgM, and IgA antibodies against SARS-CoV-2.
Ribbon diagram of the protein coat of an adeno-associated virus
Preprints Propose Constellation of Causes for Kids’ Liver Disease
Christie Wilcox | Jul 25, 2022
Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.